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Keywords = penile traction therapy

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20 pages, 315 KiB  
Review
Evidence-Based Recommendations on the Use of Immunotherapies and Monoclonal Antibodies in the Treatment of Male Reproductive Cancers
by Farhan Khalid, Zubair Hassan Bodla, Sai Rakshith Gaddameedi, Raymart Macasaet, Karan Yagnik, Zahra Niaz, Peter N. Fish, Doantrang Du and Shazia Shah
Curr. Oncol. 2025, 32(2), 108; https://doi.org/10.3390/curroncol32020108 - 14 Feb 2025
Viewed by 1366
Abstract
The incidence of male reproductive cancers, including prostate, testicular, and penile cancers, has risen in recent years, raising important health concerns. Prostate cancer is the second leading cause of cancer-related mortality in men, while penile cancer, though rare, typically affects men over 60. [...] Read more.
The incidence of male reproductive cancers, including prostate, testicular, and penile cancers, has risen in recent years, raising important health concerns. Prostate cancer is the second leading cause of cancer-related mortality in men, while penile cancer, though rare, typically affects men over 60. Testicular cancer, with a lifetime risk of about 0.4% in men, is most common among adolescents and young adults, decreasing sharply after the age of 40. Traditional treatments include chemotherapy, radiation, surgery, and combinations thereof, but advancements in immunotherapy and monoclonal antibodies are showing promising results, particularly for genitourinary cancers. These therapies, targeting immune checkpoints and tumor-specific antigens, are gaining traction as effective alternatives for resistant cases. This review provides evidence-based recommendations on current and emerging immunotherapy and monoclonal antibody treatments for male reproductive cancers, highlighting future directions to optimize patient outcomes. Full article
(This article belongs to the Section Genitourinary Oncology)
16 pages, 287 KiB  
Review
Medical Management of Peyronie’s Disease: Review of the Clinical Evidence
by Patrick Teloken and Darren Katz
Med. Sci. 2019, 7(9), 96; https://doi.org/10.3390/medsci7090096 - 18 Sep 2019
Cited by 11 | Viewed by 8690
Abstract
Peyronie’s disease is a condition that causes abnormal healing of the tunica albuginea, causing penile curvature. It is difficult to treat and its management is continuing to evolve. Proposed non-surgical treatments have included oral, topical, intralesional, extracorporeal shockwave, and traction therapy. The study [...] Read more.
Peyronie’s disease is a condition that causes abnormal healing of the tunica albuginea, causing penile curvature. It is difficult to treat and its management is continuing to evolve. Proposed non-surgical treatments have included oral, topical, intralesional, extracorporeal shockwave, and traction therapy. The study of Peyronie’s disease is made difficult by heterogeneity in the timing of presentation, severity and characteristics of deformity, and associated complaints. Moreover, meta-analyses of studies are difficult due to inconsistencies across study endpoints and the duration of treatments. This article reviews the current clinical evidence and guideline recommendations, with a focus on an improvement in penile curvature. Full article
(This article belongs to the Special Issue Men's Sexual Health)
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