Search Results (4)

This article offers a theo-phenomenological investigation of the body, exploring the dialogue between contemporary phenomenology—especially its theological turn—and Eastern Orthodox spirituality as found in the Philokalia. Building on the phenomenological distinction between body and flesh and drawing on Orthodox theology’s understanding of the body–soul unity, the article analyzes the intramundanity and finitude of the human body, as well as its transfiguration through ascetic practices and divine grace. The Incarnation of Christ is examined as a central paradigm for rethinking embodiment, revealing the eschatological promise of glorified flesh. Concepts such as ipseity, self-affection, intentionality, and counter-intentionality are employed to articulate a phenomenological vision open to theological transcendence. Ultimately, this interdisciplinary approach affirms the possibility of a body transformed by grace and destined for resurrection. Full article

The concept of anomalous self-experience, also termed Self-Disorder, has attracted both clinical and research interest, as empirical studies suggest such experiences specifically aggregate in and are a core feature of schizophrenia spectrum disorders. A comprehensive neurophenomenological understanding of Self-Disorder may improve diagnostic and therapeutic practice. This systematic review aims to evaluate anatomical, physiological, and neurocognitive correlates of Self-Disorder (SD), considered a core feature of Schizophrenia Spectrum Disorders (SSDs), towards developing a neurophenomenological understanding. A search of the PubMed database retrieved 285 articles, which were evaluated for inclusion using PRISMA guidelines. Non-experimental studies, studies with no validated measure of Self-Disorder, or those with no physiological variable were excluded. In total, 21 articles were included in the review. Findings may be interpreted in the context of triple-network theory and support a core dysfunction of signal integration within two anatomical components of the Salience Network (SN), the anterior insula and dorsal anterior cingulate cortex, which may mediate connectivity across both the Default Mode Network (DMN) and Fronto-Parietal Network (FPN). We propose a theoretical Triple-Network Model of Self-Disorder characterized by increased connectivity between the Salience Network (SN) and the DMN, increased connectivity between the SN and FPN, decreased connectivity between the DMN and FPN, and increased connectivity within both the DMN and FPN. We go on to describe translational opportunities for clinical practice and provide suggestions for future research. Full article

The purpose of my article is to shed light on the relationship of proximity and distance that linked two major figures of 20th-century French philosophy: Emmanuel Levinas and Vladimir Jankélévitch. This article presents a comparative study of their respective views on Metaphysics and Ethics. It also deals with their contribution to the reflection on the fact of “Being Jewish”, the theme that was at the center of the preoccupations of these two artisans of the renewal of Jewish thought in France after the Shoah. I conduct a comparative analysis between the key concepts of their philosophy: Levinas’ “There is” and “Otherness” and Jankélévitch’s “I-know-not-what” and “Ipseity”. I point out the difference between Levinas’ ethics of Otherness and Jankélévitch’s morality of paradox. In the section on “Being Jewish”, I highlight the crucial distinction they both made between racism and anti-Semitism and the very different meaning they gave to it. Full article

The transitioning of carbon quantum dot (cQD) applications from electrochemistry, catalysis and environmental sensing to biomedicine represents an important milestone in its 15-year history; a bellwether for its yet-unrealized potential in interventional biology, imaging, diagnostics, prophylaxis and therapy. However, despite the significant advances made over the last decade in several areas of the cQD domain, our knowledge of the exact chemical ipseity of cQDs at the Angstrom level remains either in its infancy or is largely ignored. The imminent crossing over of cQDs into biological systems and into the blood–brain barrier demands attention to the critical, yet unmet, need to resolve the inherent heterogeneity in cQD preparations and their separation into purified conformers, to identify the issues associated with potential cytotoxicity as well as to examine their bioavailability. Perhaps most importantly, and ironically neglected as well, is the compelling urgency to obtain an atomic- and molecular-level understanding of cQD’s interactions with biological receptors; a demand that requires absolute knowledge of its structure, chemistry and aspects therein. The need for the total chemical mapping of cQDs, with Angstrom-level resolution, remains the unrealized cornerstone to tailoring its specificity for its designated use in preclinical and clinical trials. Full article