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This research seeks to reduce wind-blown sand hazards in saline deserts by introducing hyperbranched PVAc copolymer emulsion as a novel ecological sand-fixing material. The study began with the preparation of the emulsion, then evaluated its fundamental properties and the salt tolerance of latex films through FTIR, SEM, and mechanical strength assessments. The sand-fixing properties (compressive strength, anti-water erosion, anti-wind erosion, thermal aging, freeze–thaw stability, and water retention) were evaluated. In addition, their effects on increasing both the growth of microbes and plants in salty deserts have been evaluated by field experiments to understand their ecological effects. The experimental results showed that the hyperbranched PVAc copolymer emulsion has excellent salt resistance and can be used as an ecological sand-fixing material in salty deserts. The research findings demonstrate that the hyperbranched PVAc copolymer emulsion exhibits superior salt tolerance, rendering it an effective ecological sand-fixing material for saline deserts. Notable attributes encompass its capacity to significantly mitigate NaCl-induced aggregate damage to sand-fixing materials, thereby enhancing sand fixation performance; its robust thermal aging resistance, freeze–thaw stability, and salt tolerance, which enable it to withstand environmental temperature variations; and experimental assessments of sand-based plant and microbial growth confirming favorable ecological impacts. This study presents novel methodologies for designing ecological sand-fixing materials in saline deserts to combat desertification. Full article