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Keywords = eucalyptus leaf extract (ELE)

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15 pages, 769 KiB  
Review
Efficacy of Topical Application of a Skin Moisturizer Containing Pseudo-Ceramide and a Eucalyptus Leaf Extract on Atopic Dermatitis: A Review
by Yutaka Takagi
J. Clin. Med. 2024, 13(6), 1749; https://doi.org/10.3390/jcm13061749 - 18 Mar 2024
Cited by 9 | Viewed by 6775
Abstract
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with pruritus, an impaired cutaneous barrier function and a disrupted water holding capacity. Levels of ceramides, which are major components of intercellular lipids and are crucial for their functions, are decreased in the [...] Read more.
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with pruritus, an impaired cutaneous barrier function and a disrupted water holding capacity. Levels of ceramides, which are major components of intercellular lipids and are crucial for their functions, are decreased in the stratum corneum of patients with AD. Treatments to increase ceramide levels are effective for AD care. Synthetic pseudo-ceramide (cetyl PG hydroxyethyl palmitamide (SLE66)), which has a structure developed via molecular designs, and a eucalyptus leaf extract (ELE) enhance ceramide synthesis in the epidermis. The topical application of a skin moisturizer containing SLE66 and ELE improves the barrier functions and water holding capacity of AD skin accompanied by an improvement in skin symptoms. This is a multifaceted review that summarizes the efficacy of the topical application of a skin moisturizer containing SLE66 and ELE on atopic dermatitis. Full article
(This article belongs to the Special Issue Clinical Updates on Atopic Dermatitis Treatment)
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13 pages, 2118 KiB  
Article
Postharvest Eucalyptus Leaf Extract Application Extends the Sustainable Supply of Strawberries by Retaining Physicochemical Quality during Cold Storage
by Muhammad Wasim Haider, Muhammad Nafees, Mohammad Valipour, Rashid Iqbal, Sajid Ali, Habat Ullah Asad, Hafiz Nazar Faried, Muhammad Aslam, Javed Iqbal and Muhammad Ayaz Shahzad
Sustainability 2022, 14(22), 14822; https://doi.org/10.3390/su142214822 - 10 Nov 2022
Cited by 8 | Viewed by 2865
Abstract
Strawberry is a delicate fruit with a short shelf life after harvest. High metabolic activities and fungal decay deteriorate its quality. In an attempt to extend its shelf life and maintain its quality while retaining its antioxidant potential, the harvested fruits of strawberry [...] Read more.
Strawberry is a delicate fruit with a short shelf life after harvest. High metabolic activities and fungal decay deteriorate its quality. In an attempt to extend its shelf life and maintain its quality while retaining its antioxidant potential, the harvested fruits of strawberry cv. Chandler were dipped in 30% eucalyptus leaf extract (ELE). Weight loss, fungal decay index, percentage of decayed fruits, respiration rate, and electrolyte leakage were all reduced in ELE-treated strawberries. The enzymatic activities of catalase in fruits increased initially until the fifth day of storage but then started to decline during the later period while superoxide dismutase and peroxidase activities continued to rise until the 10th day and then declined. With higher contents of total phenolics, ascorbic acid, total antioxidants, and anthocyanin, the application of ELE maintained the general acceptance, firmness, flavor, and marketable fruit percentage. Titrable acidity (TA) and sugar–acid ratio (SAR) were also significantly affected by ELE application. A declining trend was observed in TA during storage, along with an increase in SAR. The pH and soluble solid contents of strawberry juice were not significantly changed by the application of ELE; however, both attribute scores were greater than those for the control. In conclusion, ELE could be used as an environmentally safe method to postpone senescence and maintain postharvest quality for up to 15 days. Full article
(This article belongs to the Special Issue Sustainable Supply and Consumption of Food)
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11 pages, 1157 KiB  
Article
Oenothein B in Eucalyptus Leaf Extract Suppresses Fructose Absorption in Caco-2 Cells
by Keiichiro Sugimoto, Midori Amako, Hiroaki Takeuchi, Kazuya Nakagawa, Morio Yoshimura, Yoshiaki Amakura, Tomoyuki Fujita, Shigeo Takenaka and Hiroshi Inui
Molecules 2022, 27(1), 122; https://doi.org/10.3390/molecules27010122 - 26 Dec 2021
Cited by 5 | Viewed by 3462
Abstract
Inhibition of fructose absorption may suppress adiposity and adiposity-related diseases caused by fructose ingestion. Eucalyptus leaf extract (ELE) inhibits intestinal fructose absorption (but not glucose absorption); however, its active compound has not yet been identified. Therefore, we evaluated the inhibitory activity of ELE [...] Read more.
Inhibition of fructose absorption may suppress adiposity and adiposity-related diseases caused by fructose ingestion. Eucalyptus leaf extract (ELE) inhibits intestinal fructose absorption (but not glucose absorption); however, its active compound has not yet been identified. Therefore, we evaluated the inhibitory activity of ELE obtained from Eucalyptus globulus using an intestinal fructose permeation assay with the human intestinal epithelial cell line Caco-2. The luminal sides of a cell monolayer model cultured on membrane filters were exposed to fructose with or without the ELE. Cellular fructose permeation was evaluated by measuring the fructose concentration in the medium on the basolateral side. ELE inhibited 65% of fructose absorption at a final concentration of 1 mg/mL. Oenothein B isolated from the ELE strongly inhibited fructose absorption; the inhibition rate was 63% at a final concentration of 5 μg/mL. Oenothein B did not affect glucose absorption. In contrast, the other major constituents (i.e., gallic acid and ellagic acid) showed little fructose-inhibitory activity. To our knowledge, this is the first report that oenothein B in ELE strongly inhibits fructose absorption in vitro. ELE containing oenothein B can prevent and ameliorate obesity and other diseases caused by dietary fructose consumption. Full article
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