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Keywords = endoscopic carpal tunnel release

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17 pages, 434 KB  
Review
Evolution of Carpal Tunnel Syndrome Treatment: A Narrative Review
by Đula Đilvesi, Bojan Jelača, Aleksandar Knežević, Željko Živanović, Veljko Pantelić and Jagoš Golubović
NeuroSci 2026, 7(1), 10; https://doi.org/10.3390/neurosci7010010 - 12 Jan 2026
Abstract
Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment disorder, with a lifetime prevalence estimated at approximately 10%. This narrative review explores the historical evolution, current management strategies, and emerging trends in CTS diagnosis and treatment. Early recognition of CTS led [...] Read more.
Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment disorder, with a lifetime prevalence estimated at approximately 10%. This narrative review explores the historical evolution, current management strategies, and emerging trends in CTS diagnosis and treatment. Early recognition of CTS led to the development of conservative interventions, including splinting, corticosteroid injections, and physical therapy, aimed at alleviating median nerve compression and associated symptoms. The advent of open carpal tunnel release established surgery as the definitive treatment for moderate-to-severe CTS, with subsequent refinements—such as mini-open and endoscopic techniques—focused on minimizing tissue trauma and expediting recovery. Comparative studies demonstrate similar long-term efficacy between surgical modalities, though endoscopic approaches often provide faster short-term recovery. Advances in diagnostic imaging, including high-resolution ultrasound, have improved early detection and dynamic assessment of median nerve compression. Emerging therapies, such as regenerative biologics, neuromobilization, and minimally invasive surgical innovations, offer promising adjuncts to current care. Despite substantial progress, further research is needed to clarify optimal patient selection, refine minimally invasive techniques, and explore regenerative interventions. This review underscores the importance of individualized, evidence-based, and patient-centered approaches to CTS management, integrating both established and emerging strategies to optimize functional outcomes and quality of life. Full article
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10 pages, 1186 KB  
Article
Augmenting Patient Education in Hand Surgery—Evaluation of ChatGPT as an Informational Tool in Carpal Tunnel Syndrome
by Benedikt Fuchs, Nikolaus Thierfelder, Irene Mesas Aranda, Verena Alt, Constanze Kuhlmann, Elisabeth M. Haas-Lützenberger, Konstantin C. Koban, Riccardo E. Giunta and Sinan Mert
Medicina 2025, 61(9), 1677; https://doi.org/10.3390/medicina61091677 - 16 Sep 2025
Viewed by 1329
Abstract
Background and Objectives: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by chronic compression of the median nerve within the carpal tunnel. Patient education is a cornerstone of informed consent and postoperative outcomes, yet time constraints often limit traditional [...] Read more.
Background and Objectives: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by chronic compression of the median nerve within the carpal tunnel. Patient education is a cornerstone of informed consent and postoperative outcomes, yet time constraints often limit traditional consultations. Recently, generative AI tools such as ChatGPT have emerged as potential adjuncts in delivering standardized medical information. Materials and Methods: This study evaluated the quality and comprehensiveness of ChatGPT-generated patient education on CTS and open carpal tunnel release. A standardized prompt was used with ChatGPT-4o to generate educational material. A structured and standardized questionnaire was then administered to both patients and physicians (n = 8) to assess content quality, clarity, comprehensiveness, and perceived usefulness. Results: Both patients and physicians reported high satisfaction with the information provided. The etiology, procedural risks, and general anatomical principles were well conveyed. However, certain intraoperative concepts—such as neurolysis, synovectomy, and hemostasis—were underrepresented. While conservative therapies were addressed, the omission of endoscopic surgical options limited informational completeness. Prognostic information and long-term consequences of untreated CTS were rated as average by some participants. Postoperative guidance was adequately covered but lacked individualized nuance. Conclusions: ChatGPT shows promise as an adjunct in surgical patient education, offering clear and standardized information. Nevertheless, it is not a substitute for clinician–patient interaction. While it may bridge preliminary knowledge gaps, emotional support and individualized consent discussions remain essential. Further refinement and clinical validation of AI-generated educational content are needed to ensure safe and effective integration into routine practice. Full article
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11 pages, 1908 KB  
Article
Directly Visualized Carpal Tunnel Release via a Proximal Mini-Transverse Incision: Surgical Technique and Clinical Outcomes
by Ahmed Majid Heydar and Mustafa Kürklü
J. Clin. Med. 2025, 14(9), 3234; https://doi.org/10.3390/jcm14093234 - 7 May 2025
Cited by 1 | Viewed by 2099
Abstract
Background/Objectives: Several complications and drawbacks have been described for the endoscopic release of carpal tunnel syndrome as well as for other traditional open and mini-open release techniques. The purpose of this study was to introduce our newly developed minimally invasive technique and [...] Read more.
Background/Objectives: Several complications and drawbacks have been described for the endoscopic release of carpal tunnel syndrome as well as for other traditional open and mini-open release techniques. The purpose of this study was to introduce our newly developed minimally invasive technique and report our surgical outcomes. Methods: Seventy-five eligible patients with carpal tunnel syndrome who underwent directly visualized carpal tunnel release via proximal mini-transverse incisions were enrolled. Turkish versions of the Quick-DASH, BCTSQ, and VAS were used to quantify the functional quality and pain intensity before surgery, at the third month, and at the final follow-up. In addition, the maximum preoperative and postoperative grip strength were evaluated. Results: At the three-month follow-up, there was a significant improvement in the mean VAS score and Quick-DASH score from 5.2 ± 1.4 and 27.46 ± 7 to 1.4 ± 1.1 and 10.2 ± 3.8, respectively. Additionally, significant improvements were observed in both BCTSQ components, the SSS and FSS, with mean preoperative scores of 3.6 ± 1.2 and 3.8 ± 0.9 and postoperative scores of 1.75 ± 0.6 and 2 ± 1, respectively. The Quick-DASH, BCTSQ scores, and VAS scores were further improved at the final follow-up. The mean grip strength gradually increased from 24.2 ± 8.9 kg to 28.2 ± 2.6 kg at the final follow-up. No complications occurred during or after the operation. Conclusions: Directly visualized carpal tunnel release via a proximal mini-transverse incision is a viable option for patients with moderate to severe CTS, as it has shown high levels of satisfaction, improved grip strength, and minimal complications. Full article
(This article belongs to the Section Orthopedics)
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2 pages, 623 KB  
Correction
Correction: Yamamoto et al. Trends in Open vs. Endoscopic Carpal Tunnel Release: A Comprehensive Survey in Japan. J. Clin. Med. 2022, 11, 4966
by Michiro Yamamoto, James Curley and Hitoshi Hirata
J. Clin. Med. 2023, 12(6), 2223; https://doi.org/10.3390/jcm12062223 - 13 Mar 2023
Viewed by 1174
Abstract
In the original publication [...] Full article
(This article belongs to the Special Issue Recent Research of Carpal Tunnel Syndrome)
10 pages, 2287 KB  
Article
Trends in Open vs. Endoscopic Carpal Tunnel Release: A Comprehensive Survey in Japan
by Michiro Yamamoto, James Curley and Hitoshi Hirata
J. Clin. Med. 2022, 11(17), 4966; https://doi.org/10.3390/jcm11174966 - 24 Aug 2022
Cited by 8 | Viewed by 3532 | Correction
Abstract
We analyzed trends in open and endoscopic carpal tunnel release (CTR) from 2014 to 2019 using the National Database of Health Insurance Claims and Specific Health Checkups in Japan (NDB). Japan has a universal health insurance system and more than 95% of all [...] Read more.
We analyzed trends in open and endoscopic carpal tunnel release (CTR) from 2014 to 2019 using the National Database of Health Insurance Claims and Specific Health Checkups in Japan (NDB). Japan has a universal health insurance system and more than 95% of all claims are searchable in the NDB open data repository. The results revealed that nearly 40,000 CTRs were performed annually in Japan, and open CTR was performed almost 4 times more often than endoscopic CTR. The crude annual incidence of CTR in the general population among people 20 years of age or older was 32.2 per 100,000. The incidence of open CTR peaked in the 80–84 age range for both males and females. The incidence of endoscopic CTR peaked at 80–84 years in females and at 75–79 years in males. There was a mild correlation coefficient between the endoscopic CTRs and the number of hand surgery specialists by prefecture per population (r = 0.32, p = 0.04). However, the number of hand surgeons per capita by region and open CTR per capita was not correlated (r = 0.06, p = 0.67). There were about twice as many outpatient as inpatient surgeries, reflecting a trend toward ambulatory treatment. Full article
(This article belongs to the Special Issue Recent Research of Carpal Tunnel Syndrome)
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15 pages, 1498 KB  
Review
Compression Neuropathies of the Upper Extremity: A Review
by Carter J. Boyd, Nikhi P. Singh, Joseph X. Robin and Sheel Sharma
Surgeries 2021, 2(3), 320-334; https://doi.org/10.3390/surgeries2030032 - 2 Sep 2021
Cited by 13 | Viewed by 9270
Abstract
Compressive neuropathies of the forearm are common and involve structures innervated by the median, ulnar, and radial nerves. A thorough patient history, occupational history, and physical examination can aid diagnosis. Electromyography, X-ray, and Magnetic Resonance Imaging may prove useful in select syndromes. Generally, [...] Read more.
Compressive neuropathies of the forearm are common and involve structures innervated by the median, ulnar, and radial nerves. A thorough patient history, occupational history, and physical examination can aid diagnosis. Electromyography, X-ray, and Magnetic Resonance Imaging may prove useful in select syndromes. Generally, first line therapy of all compressive neuropathies consists of activity modification, rest, splinting, and non-steroidal anti-inflammatory drugs. Many patients experience improvement with conservative measures. For those lacking adequate response, steroid injections may improve symptoms. Surgical release is the last line therapy and has varied outcomes depending on the compression. Carpal Tunnel syndrome (CTS) is the most common, followed by ulnar tunnel syndrome. Open and endoscopic CTS release appear to have similar outcomes. Endoscopic release appears to incur decreased cost baring a low rate of complications, although this is debated in the literature. Additional syndromes of median nerve compression include pronator syndrome (PS), anterior interosseous syndrome, and ligament of Struthers syndrome. Ulnar nerve compressive neuropathies include cubital tunnel syndrome and Guyon’s canal. Radial nerve compressive neuropathies include radial tunnel syndrome and Wartenberg’s syndrome. The goal of this review is to provide all clinicians with guidance on diagnosis and treatment of commonly encountered compressive neuropathies of the forearm. Full article
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