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Keywords = enantiopurification

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11 pages, 3370 KiB  
Article
Enantiopurification by Co-Crystallization within Cyclodextrin Metal–Organic Framework
by Masoud Kazem-Rostami, Pardis Shirdast and Kalidas Mainali
Crystals 2024, 14(6), 568; https://doi.org/10.3390/cryst14060568 - 19 Jun 2024
Cited by 1 | Viewed by 1694
Abstract
Tröger’s base analogs (TBAs) and their derivatives are versatile, Λ-shaped, tetracyclic chiral building blocks utilized in numerous fields of research. Although various methods for the enantiopurification of TBAs have been demonstrated in the literature, none has achieved it with the use of metal–organic [...] Read more.
Tröger’s base analogs (TBAs) and their derivatives are versatile, Λ-shaped, tetracyclic chiral building blocks utilized in numerous fields of research. Although various methods for the enantiopurification of TBAs have been demonstrated in the literature, none has achieved it with the use of metal–organic frameworks (MOFs). This investigation introduces a convenient and scalable method to obtain enantiopure TBAs with the formation and digestion of a chiral MOF composed of fully recoverable and non-hazardous starting materials, namely, cyclodextrin-based metal–organic framework (CD-MOF). Full article
(This article belongs to the Section Organic Crystalline Materials)
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