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Keywords = early parenthood

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14 pages, 280 KiB  
Review
Workplace Discrimination Against Pregnant and Postpartum Employees: Links to Well-Being
by Kimberly T. Schneider, Sarah C. Williams and Rory E. Kuhn
Int. J. Environ. Res. Public Health 2025, 22(8), 1160; https://doi.org/10.3390/ijerph22081160 - 22 Jul 2025
Viewed by 702
Abstract
Pregnancy-related discrimination at work is a concern for many employees who navigate the pregnancy and postpartum stages of parenthood while working in the early-to-middle stages of their careers. Although there is legislation prohibiting pregnancy-related discrimination and ensuring accommodations postpartum, empirical evidence indicates many [...] Read more.
Pregnancy-related discrimination at work is a concern for many employees who navigate the pregnancy and postpartum stages of parenthood while working in the early-to-middle stages of their careers. Although there is legislation prohibiting pregnancy-related discrimination and ensuring accommodations postpartum, empirical evidence indicates many pregnant and postpartum employees still experience such behaviors. In this narrative review, we focus on describing the range of behaviors assessed in studies on pregnancy-related discrimination in several cultures, situating the occurrence of discrimination within theoretical frameworks related to stereotypes and gendered expectations. We also review evidence of employees’ postpartum experiences with a focus on the transition back to work, along with breastfeeding challenges related to pumping and storing milk at work. Regarding coping with pregnancy-related workplace discrimination and postpartum challenges during a return to work, we review the importance of social support, including instrumental and emotional support from allies and role models. Full article
(This article belongs to the Special Issue How Reproductive Life Events Influence Women's Mental Health)
10 pages, 720 KiB  
Article
Exploring Partners, Parenting and Pregnancy Thinking in Late Adolescents and Young Adults with Inherited Metabolic Disorders
by Albina Tummolo, Giulia Paterno, Rosa Carella, Livio Melpignano and Donatella De Giovanni
Pediatr. Rep. 2025, 17(3), 56; https://doi.org/10.3390/pediatric17030056 - 13 May 2025
Viewed by 298
Abstract
Introduction: The psychosocial impact of living with an Inherited Metabolic Disorder (IMD) is becoming increasingly relevant and can have a significant impact on planning the future, conditioning the reproductive decisions made during adolescence and young adulthood. The aim of this paper is to [...] Read more.
Introduction: The psychosocial impact of living with an Inherited Metabolic Disorder (IMD) is becoming increasingly relevant and can have a significant impact on planning the future, conditioning the reproductive decisions made during adolescence and young adulthood. The aim of this paper is to explore thoughts about partner choices, parenthood and pregnancy among adolescents and young adults affected by IMDs. Methods: A cross-sectional study was performed. A sample of 23 patients affected by a range of IMDs were interviewed. Twenty-two questions were provided, distinguished into four main themes: partners, parenthood, pregnancy and need for information. Results: More than half of participants (57%) reported insecurities about relationships and declared that they were single for this reason, with most (70%) having a hope of having children in the future, although with the awareness and fear that they could also be affected. Almost all females (90%) consider themselves able to carry a pregnancy in a way similar to other women. There was the common need for more information about their potential fertility and parenthood linked to their condition. Conclusion: Being diagnosed with an IMD can influence personal decisions regarding relationships and reproduction. The early identification of issues in these domains may enhance referrals for personalized interventions and build more focused support programmes. Full article
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15 pages, 276 KiB  
Article
Mother–Infant Relational Quality Following a NICU Stay: Investigating the Role of Maternal Childhood Experiences
by Corinna C. Klein, Camila A. Ferrario, Ying Yan and Nicole M. McDonald
Int. J. Environ. Res. Public Health 2025, 22(5), 732; https://doi.org/10.3390/ijerph22050732 - 3 May 2025
Viewed by 717
Abstract
A Neonatal Intensive Care Unit (NICU) stay complicates the transition to parenthood for new mothers. Women respond differently to perinatal stressors, which can impact their mental health and relationship with their new baby. Mothers’ own histories of adverse and benevolent childhood experiences can [...] Read more.
A Neonatal Intensive Care Unit (NICU) stay complicates the transition to parenthood for new mothers. Women respond differently to perinatal stressors, which can impact their mental health and relationship with their new baby. Mothers’ own histories of adverse and benevolent childhood experiences can also shape their early parenting experiences. This study investigated the relationship between mothers’ adverse and benevolent childhood experiences and the observed and reported quality of interactions with their infant at 1 year following a NICU stay. Somewhat unexpectedly, we found that more maternal childhood adversity predicted less intrusive behavior and more responsiveness during a free play interaction at 12 months, while more benevolent childhood experiences predicted higher levels of observed intrusive mothering. Childhood experiences were not related to maternal perceptions of parent–child interaction quality. The length of the NICU stay was positively associated with maternal responsiveness. Findings highlight that childhood risk and protective factors may interact uniquely with a stay in the NICU, with greater adversity and a longer stay predicting more maternal responsiveness and sensitivity. Our study offers evidence that mothers can overcome their own early life challenges, and that overcoming childhood adversity may build resilience that uniquely prepares mothers for the challenge of a NICU stay. Full article
(This article belongs to the Special Issue How Reproductive Life Events Influence Women's Mental Health)
18 pages, 247 KiB  
Article
Doing Everything We Can to Help Our High-Risk Newborns: A Qualitative, Lifeworld-Led Study of What Early Risk Assessment for Cerebral Palsy Means to Parents
by Kristin Bjørnstad Åberg, Karin Dahlberg, Gunfrid Vinje Størvold, Ragnhild Støen and Lars Adde
J. Clin. Med. 2025, 14(8), 2740; https://doi.org/10.3390/jcm14082740 - 16 Apr 2025
Viewed by 600
Abstract
Background/Objectives: Early predictive assessments for CP are recommended for infants with medical risk factors after birth. For parents of children with CP, receiving an early diagnosis is important. But most children with risk factors who have not yet developed CP are labeled “high-risk [...] Read more.
Background/Objectives: Early predictive assessments for CP are recommended for infants with medical risk factors after birth. For parents of children with CP, receiving an early diagnosis is important. But most children with risk factors who have not yet developed CP are labeled “high-risk infants” and repeatedly assessed for abnormal signs. We aim to investigate the experience of parents of high-risk infants and describe the meaning that “early predictive assessments for CP” has for them before they know whether their children have CP. Methods: This was a qualitative study conducted using a phenomenological, reflective lifeworld approach. Fourteen individual in-depth interviews were conducted with parents who received different GMA results to learn about their experiences involving early predictive assessments. The interviews were analyzed for meaning. Results: Early predictive assessments take place over time while parents process the traumatic experience of becoming parents to an infant at risk. “Early predictive assessment” is perceived as any examination or assessment intended to unveil signs of illness or disability. The child’s future well-being and fulfillment, and the demands of parenthood, are at stake. Essential meaning structures are (1) on a spectrum from death to insignificancies, (2) living with uncertainty of what the parental role will entail, and (3) seeing one’s own child through the eyes of strangers, just in case. Conclusions: For months following the birth of a high-risk child, parents experience uncertainty and worrying, affecting the parent–infant relationship. Predictive assessments reduce their sense of alarm when the GMA result indicates a low risk of CP. But when the GMA result is uncertain, the burden of uncertainty is amplified and prolonged. Full article
12 pages, 559 KiB  
Systematic Review
Attention Deficit Hyperactivity Disorder in Girls and the Risk of Unplanned Pregnancies
by Florina Rad, Alexandra Mariana Buică and Nicolae Gică
Children 2025, 12(1), 62; https://doi.org/10.3390/children12010062 - 7 Jan 2025
Viewed by 1564
Abstract
Background/Objectives: Although ADHD in adults has become visible and inclusive in recent years in diagnostic manuals, research is still limited regarding the long-term outcomes of patients with this disorder. The main objective of this research was to address the many facets of predictor [...] Read more.
Background/Objectives: Although ADHD in adults has become visible and inclusive in recent years in diagnostic manuals, research is still limited regarding the long-term outcomes of patients with this disorder. The main objective of this research was to address the many facets of predictor variables in girls with ADHD facing unplanned pregnancies at young ages in order to improve the management of pre-, peri-, and postnatal complications that may occur, as well as for early psychiatric diagnosis and effective intervention. Methods: PubMed and Web of Science Databases were used to perform literature research, and a total of 27 records were selected and used for data extraction. Results: Related articles have included the persistence of ADHD symptoms comorbid with other disorders among girls with ADHD as a risk factor for teenage pregnancies. Conduct disorders and substance use disorders are the main co-occurrent diagnoses that increase the likelihood for teenage childbirth. Unplanned pregnancies at young ages are associated with unfavorable psychosocial trajectories both for the mother and the child. Conclusions: In this review, we emphasize the importance of predisposing factors for risky sexual behaviors and unplanned pregnancies in cases of girls with ADHD. The topic of the article draws attention to the need for uniform national individualized care of girls with ADHD, the implementation of programs to prevent academic failure and early parenthood as well as addressing comorbid obstetrical and psychiatric conditions, especially in regions where the rate of adolescent births continues to be high. Full article
(This article belongs to the Special Issue New Insights in Pediatric Mental Healthcare)
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14 pages, 333 KiB  
Article
First-Time Parents’ Bonding with Their Baby: A Longitudinal Study on Finnish Parents during the First Eight Months of Parenthood
by Jessica Toivo, Noora Tulivuo, Mitsuko Kanzaki, Anna-Maija Koivisto, Jari Kylmä and Eija Paavilainen
Children 2023, 10(11), 1806; https://doi.org/10.3390/children10111806 - 14 Nov 2023
Cited by 2 | Viewed by 3122
Abstract
Early positive bonding between parents and babies promotes the development of parenting skills and parents’ sensitivity to their infant’s needs. Positive bonding has been suggested to decrease the risk of maltreatment. There is less research into the differences between primiparae’s and their spouses’ [...] Read more.
Early positive bonding between parents and babies promotes the development of parenting skills and parents’ sensitivity to their infant’s needs. Positive bonding has been suggested to decrease the risk of maltreatment. There is less research into the differences between primiparae’s and their spouses’ bonding with their baby and changes in the parent-to-infant bonding during the first year of the baby’s life. The aim of this study was to describe bonding with one’s baby and related differences and changes within first-time parents. The data were collected from nine maternal health clinics in 2019–2021 in one city in Finland. The Mother-to-Infant Bonding Scale (MIBS) and the Edinburgh Postnatal Depression Scale (EPDS) were used. The data were collected during pregnancy (T1) and when the baby was aged 1–2 months (T2) and 6–8 months (T3). The questionnaire was completed separately by the primiparae (n = 81 at T1) and their spouses (n = 79 at T1). The findings demonstrated that both parents had positive feelings for their baby. The primiparae’s and their spouses’ MIBS scores were relatively low at T2 and T3. The change between time points or the difference in the parents’ bonding was not statistically significant when examining MIBS total scores. The present study identified a positive weak-to-moderate correlation between the MIBS and EPDS. This association was highlighted in the group of primiparae. The results of this study can be used to develop maternity and child health clinic services, and to promote parents’ equal growth in parenthood. Full article
(This article belongs to the Section Pediatric Nursing)
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13 pages, 572 KiB  
Article
Long-Term Effects of Maternal Depression during Postpartum and Early Parenthood Period on Child Socioemotional Development
by Anna Suarez, Liubov Shraibman and Vera Yakupova
Children 2023, 10(10), 1718; https://doi.org/10.3390/children10101718 - 23 Oct 2023
Cited by 10 | Viewed by 5697
Abstract
Most research on the impact of maternal depressive symptoms on child development is conducted during the first year postpartum. Findings on long-term effects of maternal depression are still contradictory and underexplored. The present study investigates the long-term impact of maternal depression during the [...] Read more.
Most research on the impact of maternal depressive symptoms on child development is conducted during the first year postpartum. Findings on long-term effects of maternal depression are still contradictory and underexplored. The present study investigates the long-term impact of maternal depression during the postpartum and early parenthood periods on child behavioral problems at the mean age of 2.25 years. The Edinburgh postnatal depression scale and Beck depression Inventory were used to assess postpartum and early parenthood depression, respectively. The Child Behavior Checklist was used to examine child’s behavioral problems. The regression analysis showed statistically significant associations between child behavioral problems and maternal depression during early parenthood and no significant associations with postpartum depression. Four maternal depressive symptoms’ trajectories were identified: consistently low, consistently high, decreased, and increased. The children of mothers with consistently high depressive symptoms at both research stages had the most significant total, internalizing, and externalizing problems. Children of mothers whose depressive symptoms decreased over time had the lowest scores in all three domains of behavioral problems. It is extremely important to implement programs for screening and early intervention for maternal mental health problems that could greatly influence the well-being of women and their children’s development. Full article
(This article belongs to the Special Issue Updates on Perinatal Depression and Child Developmental Disorders)
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22 pages, 570 KiB  
Systematic Review
Seeking Health in a Digital World: Exploring Immigrant Parents’ Quest for Child Health Information—A Scoping Review
by Annina E. Zysset, Patricia Schwärzler and Julia Dratva
Int. J. Environ. Res. Public Health 2023, 20(19), 6804; https://doi.org/10.3390/ijerph20196804 - 22 Sep 2023
Cited by 2 | Viewed by 2978
Abstract
During pregnancy and early parenthood, parents’ strong interest in pediatric health information presents a valuable opportunity to positively impact long-term health-seeking behavior and overall child health. In line with the increasing prevalence of digital transformation, a scoping review was conducted to explore two [...] Read more.
During pregnancy and early parenthood, parents’ strong interest in pediatric health information presents a valuable opportunity to positively impact long-term health-seeking behavior and overall child health. In line with the increasing prevalence of digital transformation, a scoping review was conducted to explore two key aspects: (1) information seeking and use of digital health information among immigrant parents, and (2) associated reasons and factors. The literature search covered the period until July 2022, using Web of Science, MEDLINE, and CINAHL Complete databases. Out of 625 articles, 12 were included, comprising six qualitative, five quantitative studies, and one review. The majority of studies focused on immigrants in North America, primarily from Latin America and Asia. The studies varied in topics and methodologies, making it challenging to draw general conclusions. Nevertheless, while most immigrant parents rely on digital information on child health, they often prefer human sources such as family, friends, or healthcare providers. Trustworthiness and accessibility emerged as critical criteria for health resources. Two focus group discussions, derived from the results of the review, confirmed these findings for migrant mothers in Switzerland. Full article
(This article belongs to the Section Digital Health)
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19 pages, 1169 KiB  
Article
Paid Parental Leave in Correlation with Changing Gender Role Attitudes
by Gerlinde Mauerer
Soc. Sci. 2023, 12(9), 490; https://doi.org/10.3390/socsci12090490 - 31 Aug 2023
Cited by 4 | Viewed by 4164
Abstract
In recent decades, several countries have implemented paid parental leave for parents. This paper discusses the correlation between paid parental leave—which in Austria corresponds with receiving childcare benefits—and changing gender role attitudes in different-gender parent couples. It draws on evidence from 42 semi-structured [...] Read more.
In recent decades, several countries have implemented paid parental leave for parents. This paper discusses the correlation between paid parental leave—which in Austria corresponds with receiving childcare benefits—and changing gender role attitudes in different-gender parent couples. It draws on evidence from 42 semi-structured couple interviews (n = 42, 2021–2022) in which couples were asked how they arranged childcare, employment, and household chores and how they reached agreements with employers. The empirical data were first analyzed based on content and then by applying constructivist-informed grounded theory to investigate whether and how gender affected couples’ efforts to reconcile childcare, employment, and household chores and how employers responded to parental arrangements that challenged traditional gender role attitudes. Compared to other countries, Austria offers rather generous childcare benefits, including long leave periods. In addition, Austria has introduced a partnership bonus for parents who share childcare benefits 50:50 or 60:40. However, the number of couples who take advantage of these benefits is still low. In the presented research, parents who succeeded in sharing these childcare benefits were interviewed. All interviewees had taken at least five months of paid parental leave. The data were analyzed using a content-oriented approach and by applying informed grounded theory. The results show that a substantial number of fathers continued working in minor employment while receiving childcare benefits, in line with the prevailing assumption among employers that the man is the main family breadwinner. By contrast, mothers had to strongly insist that they could continue working during the early transition to parenthood. However, on an individual level and in specific domains, Austrian parents were able to successfully overcome traditional gender inequalities in reconciling work and family with the support of the newly implemented childcare benefits. The observation that in Austria, the share of fathers who take the income-related form of parental leave is higher than that of fathers who claim other forms of childcare benefits points to the importance of all parents having access to well-compensated parental leave, regardless of their income level before the birth of a child. Full article
(This article belongs to the Special Issue “Non-Traditional” Parents in Contemporary Societies)
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12 pages, 274 KiB  
Article
Parental Burnout in the Context of Special Needs, Adoption, and Single Parenthood
by Isabelle Roskam and Moïra Mikolajczak
Children 2023, 10(7), 1131; https://doi.org/10.3390/children10071131 - 29 Jun 2023
Cited by 7 | Viewed by 3930
Abstract
Although early work on parental burnout in the 1980s did not link parental burnout to specific parenting situations, the idea that parents affected by specific vulnerability factors were particularly at risk of burnout quickly emerged. Based on the etiological model of parental burnout [...] Read more.
Although early work on parental burnout in the 1980s did not link parental burnout to specific parenting situations, the idea that parents affected by specific vulnerability factors were particularly at risk of burnout quickly emerged. Based on the etiological model of parental burnout (i.e., the balance between risks and resources), the objective of this study was to investigate if there were specific vulnerability factors that significantly increase the risk of parental burnout. 2563 parents participated in the study. We compared parents with a child with special needs (n = 25), parents who had adopted a child (n = 130), and single parents (n = 109), to strictly matched control groups of parents. Parents with a child with special needs displayed higher burnout and lower balance between risk and resources than the control group; parents with an adopted child had similar levels of both parental burnout and balance; and single parents had higher parental burnout but similar balance. Parents who combined specific several vulnerability factors were at greater risk of burnout. Single parenthood and adoption do not in themselves trigger a process leading de facto to other risk factors, but having a child with special needs does. Full article
19 pages, 2531 KiB  
Article
Gender Gaps in Mode Usage, Vehicle Ownership, and Spatial Mobility When Entering Parenthood: A Life Course Perspective
by Hung-Chia Yang, Ling Jin, Alina Lazar, Annika Todd-Blick, Alex Sim, Kesheng Wu, Qianmiao Chen and C. Anna Spurlock
Systems 2023, 11(6), 314; https://doi.org/10.3390/systems11060314 - 20 Jun 2023
Cited by 7 | Viewed by 2928
Abstract
Entry into parenthood is a major disruptive event to travel behavior, and gender gaps in mobility choices are often widened during parenthood. The exact timing of gender gap formation and their long-term effects on different subpopulations are less studied in the literature. Leveraging [...] Read more.
Entry into parenthood is a major disruptive event to travel behavior, and gender gaps in mobility choices are often widened during parenthood. The exact timing of gender gap formation and their long-term effects on different subpopulations are less studied in the literature. Leveraging a longitudinal dataset from the 2018 WholeTraveler Study, this paper examines the effects of parenthood on a diverse set of short- to long-term outcomes related to the three hierarchical domains of mobility biography: mode choice, vehicle ownership, spatial mobility, and career decisions. The progress of the effects is evaluated over a sequential set of parenting stages and differentiated across three subpopulations. We find that individuals classified as “Have-it-alls”, who start their careers, partner up, and have children concurrently and early, significantly increase their car uses two years prior to childbirth (“nesting period”), and they then relocate to less transit-accessible areas and consequently reduce their reliance on public transportation while they have children in the household. In contrast, individuals categorized as “Couples”, who start careers and partnerships early but delay parenthood, and “Singles”, who postpone partnership and parenthood, have less pronounced changes in travel behavior throughout the parenting stages. The cohort-level effects are found to be driven primarily by women, whose career development is on average more negatively impacted by parenting events than men, regardless of their life course trajectory. Early career decisions made by women upon entering parenthood contribute to gender gaps in mid- to longer-term mobility decisions, signifying the importance of early intervention. Full article
(This article belongs to the Special Issue Decision Making and Policy Analysis in Transportation Planning)
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11 pages, 282 KiB  
Article
The Assessment of Natural Vaginal Delivery in Relation to Pregnancy-Related Anxiety—A Single-Center Pilot Study
by Anna Michalik, Michalina Pracowity and Lucyna Wójcicka
Healthcare 2023, 11(10), 1435; https://doi.org/10.3390/healthcare11101435 - 15 May 2023
Viewed by 1839
Abstract
Background: Pregnancy-related anxiety (PrA) is a specific type of anxiety experienced during the perinatal period. It may concern a person’s health and physical appearance, fetal development, hospital and health care experiences, impending childbirth, and early parenthood. PrA is considered to be a stronger [...] Read more.
Background: Pregnancy-related anxiety (PrA) is a specific type of anxiety experienced during the perinatal period. It may concern a person’s health and physical appearance, fetal development, hospital and health care experiences, impending childbirth, and early parenthood. PrA is considered to be a stronger predictor of adverse pregnancy outcomes than general anxiety and depression. The purpose of this research was to conduct a pilot study and evaluate the course of vaginal birth (VB) in relation to PrA levels in a population of pregnant women with low obstetrical risk. Methods: This cross-sectional exploratory study included 84 pregnant women (with a mean age of 28.61 ± 4.99) (without cesarean section (CS) indications and with a low risk of complications during VB). Research questionnaires were distributed and filled in in person during the course of hospitalization. Groups that varied at the level of PrA were compared using the Wilcoxon rank-sum test, Fisher’s exact test, or chi-square test of independence, as appropriate. Results: More than two-thirds of the respondents (72.6%) were medicated in labor. Women with high PrA, selected based on a cut-off point with a total PRAQ-R2 score of 60, experienced significantly longer first (start of established labor to fully dilated cervix) and second (lasts from when cervix is fully dilated until the birth) periods of labor, instrumental delivery, or emergency CS. In the group with high PrA levels, a episiotMmentation of evidence-based recommendations for the affected population to identify and further treat women with elevated levels of PrA. Full article
16 pages, 1444 KiB  
Article
Recommendations for the Development of Family-Based Interventions Aiming to Prevent Unhealthy Changes in Energy Balance-Related Behavior during the Transition to Parenthood: A Focus Group Study
by Vickà Versele, Benedicte Deforche, Dirk Aerenhouts, Peter Clarys, Roland Devlieger, Annick Bogaerts, Christoph Liel, Johanna Löchner, Jörg Wolstein, Mireille van Poppel and Tom Deliens
Nutrients 2022, 14(11), 2346; https://doi.org/10.3390/nu14112346 - 4 Jun 2022
Cited by 6 | Viewed by 3255
Abstract
Feasible interventions addressing unhealthy changes in energy balance-related behavior (EBRB) during pregnancy and early postpartum are needed. This study identified the needs and wishes of expecting and first-time parents concerning EBRB interventions during the transition to parenthood. Thirteen focus group discussions (n = [...] Read more.
Feasible interventions addressing unhealthy changes in energy balance-related behavior (EBRB) during pregnancy and early postpartum are needed. This study identified the needs and wishes of expecting and first-time parents concerning EBRB interventions during the transition to parenthood. Thirteen focus group discussions (n = 74) were conducted. Couples provided information about whether an intervention targeting unhealthy EBRB changes during pregnancy and postpartum would be acceptable, how such an intervention should look like, and in which way and during which period they needed support. Guided by the TiDIER checklist, all quotes were divided into five main categories (i.e., ‘what’, ‘how’, ‘when and how much’, ‘where’, ‘for and from whom’). Interventions should aim for changes at the individual, social, environmental and policy levels. The accessibility and approach (indirect or face-to-face) together with communicational aspects should be taken into account. A focus should go to delivering reliable and personalized information and improving self-regulation skills. Interventions should be couple- or family-based. Authorities, healthcare professionals, the partner and peers are important sources for intervention delivery and support. In the prevention of unhealthy EBRB changes around childbirth, the involvement of both parents is needed, while health care professionals play an important role in providing personalized advice. Full article
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20 pages, 1878 KiB  
Review
Biomolecular and Genetic Prognostic Factors That Can Facilitate Fertility-Sparing Treatment (FST) Decision Making in Early Stage Endometrial Cancer (ES-EC): A Systematic Review
by Panayiotis Tanos, Savvas Dimitriou, Giuseppe Gullo and Vasilios Tanos
Int. J. Mol. Sci. 2022, 23(5), 2653; https://doi.org/10.3390/ijms23052653 - 28 Feb 2022
Cited by 46 | Viewed by 4653
Abstract
Endometrial cancer occurs in up to 29% of women before 40 years of age. Seventy percent of these patients are nulliparous at the time. Decision making regarding fertility preservation in early stage endometrial cancer (ES-EC) is, therefore, a big challenge since the decision [...] Read more.
Endometrial cancer occurs in up to 29% of women before 40 years of age. Seventy percent of these patients are nulliparous at the time. Decision making regarding fertility preservation in early stage endometrial cancer (ES-EC) is, therefore, a big challenge since the decision between the risk of cancer progression and a chance to parenthood needs to be made. Sixty-two percent of women with complete remission of ES-EC after fertility-sparing treatment (FST) report to have a pregnancy wish which, if not for FST, they would not be able to fulfil. The aim of this review was to identify and summarise the currently established biomolecular and genetic prognostic factors that can facilitate decision making for FST in ES-EC. A comprehensive search strategy was carried out across four databases; Cochrane, Embase, MEDLINE, and PubMed; they were searched between March 1946 and 22nd December 2022. Thirty-four studies were included in this study which was conducted in line with the PRISMA criteria checklist. The final 34 articles encompassed 9165 patients. The studies were assessed using the Critical Appraisal Skills Program (CASP). PTEN and POLE alterations we found to be good prognostic factors of ES-EC, favouring FST. MSI, CTNNB1, and K-RAS alterations were found to be fair prognostic factors of ES-EC, favouring FST but carrying a risk of recurrence. PIK3CA, HER2, ARID1A, P53, L1CAM, and FGFR2 were found to be poor prognostic factors of ES-EC and therefore do not favour FST. Clinical trials with bigger cohorts are needed to further validate the fair genetic prognostic factors. Using the aforementioned good and poor genetic prognostic factors, we can make more confident decisions on FST in ES-EC. Full article
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12 pages, 619 KiB  
Article
“Nobody Listened”. Mothers’ Experiences and Needs Regarding Professional Support Prior to Their Admission to an Infant Mental Health Day Clinic
by Tinne Nuyts, Sarah Van Haeken, Neeltje Crombag, Binu Singh, Susan Ayers, Susan Garthus-Niegel, Marijke Anne Katrien Alberta Braeken and Annick Bogaerts
Int. J. Environ. Res. Public Health 2021, 18(20), 10917; https://doi.org/10.3390/ijerph182010917 - 17 Oct 2021
Cited by 7 | Viewed by 4418
Abstract
Challenges during the perinatal period can lead to maternal distress, negatively affecting mother-infant interaction. This study aims to retrospectively explore the experiences and needs regarding professional support of mothers with difficulties in mother-infant interaction prior to their admission to an infant mental health [...] Read more.
Challenges during the perinatal period can lead to maternal distress, negatively affecting mother-infant interaction. This study aims to retrospectively explore the experiences and needs regarding professional support of mothers with difficulties in mother-infant interaction prior to their admission to an infant mental health day clinic. In-depth semi-structured interviews were conducted with 13 mothers who had accessed an infant mental health day clinic because of persistent severe infant regulatory problems impairing the wellbeing of the infant and the family. Data were transcribed and analyzed using the Qualitative Analysis Guide of Leuven (QUAGOL). Three themes were identified: ‘experience of pregnancy, birth, and parenthood’; ‘difficult care paths’; and ‘needs and their fulfillment’. The first theme consisted of three subthemes: (1) ‘reality does not meet expectations’, (2) ‘resilience under pressure’, and (3) ‘despair’. Mothers experienced negative feelings that were in contradiction to the expected positive emotions associated with childbirth and motherhood. Resilience-related problems affected the mother-child relationship, and infants’ regulatory capacities. Determined to find solutions, different healthcare providers were consulted. Mothers’ search for help was complex and communication between healthcare providers was limited because of a fragmented care provision. This hindered the continuity of care and appropriate referrals. Another pitfall was the lack of a broader approach, with the emphasis on the medical aspects without attention to the mother-child dyad. An integrated care pathway focusing on the early detection of resilience-related problems and sufficient social support can be crucial in the prevention and early detection of perinatal and infant mental health problems. Full article
(This article belongs to the Special Issue Frontiers in Perinatal Mental Health)
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