Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = co-axial centrifugal spinning

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
19 pages, 36571 KB  
Article
Multi-Functional Core-Shell Nanofibers for Wound Healing
by Zhen Li, Shunqi Mei, Yajie Dong, Fenghua She, Puwang Li, Yongzhen Li and Lingxue Kong
Nanomaterials 2021, 11(6), 1546; https://doi.org/10.3390/nano11061546 - 11 Jun 2021
Cited by 23 | Viewed by 4647
Abstract
Core-shell nanofibers have great potential for bio-medical applications such as wound healing dressings where multiple drugs and growth factors are expected to be delivered at different healing phases. Compared to monoaxial nanofibers, core-shell nanofibers can control the drug release profile easier, providing sustainable [...] Read more.
Core-shell nanofibers have great potential for bio-medical applications such as wound healing dressings where multiple drugs and growth factors are expected to be delivered at different healing phases. Compared to monoaxial nanofibers, core-shell nanofibers can control the drug release profile easier, providing sustainable and effective drugs and growth factors for wound healing. However, it is challenging to produce core-shell structured nanofibers with a high production rate at low energy consumption. Co-axial centrifugal spinning is an alternative method to address the above limitations to produce core-shell nanofibers effectively. In this study, a co-axial centrifugal spinning device was designed and assembled to produce core-shell nanofibers for controlling the release rate of ibuprofen and hEGF in inflammation and proliferation phases during the wound healing process. Core-shell structured nanofibers were confirmed by TEM. This work demonstrated that the co-axial centrifugal spinning is a high productivity process that can produce materials with a 3D environment mimicking natural tissue scaffold, and the specific drug can be loaded into different layers to control the drug release rate to improve the drug efficiency and promote wound healing. Full article
Show Figures

Figure 1

Back to TopTop