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4 Results Found

  • Article
  • Open Access
12 Citations
3,038 Views
11 Pages

31 August 2022

Prothymosin α (PTMA) is a phylogenetically conserved polypeptide in male gonads of Vertebrates. In Mammals, it is a ubiquitous protein, and, possessing a random-coil structure, it interacts with many other partners, in both cytoplasmic and nucl...

  • Communication
  • Open Access
7 Citations
2,827 Views
13 Pages

Herein, for the first time, the potential relationships between the cytoskeleton-associated proteins DAAM1 and PREP with different testicular disorders, such as classic seminoma (CS), Leydig cell tumor (LCT), and Sertoli cell-only syndrome (SOS), wer...

  • Article
  • Open Access
30 Citations
9,564 Views
16 Pages

Genetic Variants of GPER/GPR30, a Novel Estrogen-Related G Protein Receptor, Are Associated with Human Seminoma

  • Nicolas Chevalier,
  • Rachel Paul-Bellon,
  • Philippe Camparo,
  • Jean-François Michiels,
  • Daniel Chevallier and
  • Patrick Fénichel

21 January 2014

Testicular germ cell tumors (TGCTs) are the most common solid cancers in young men, with an increasing incidence over several years. However, their pathogenesis remains a matter of debate. Some epidemiological data suggest the involvement of both en...

  • Article
  • Open Access
17 Citations
3,275 Views
23 Pages

Testicular Neoplasms: Primary Tumour Size Is Closely Interrelated with Histology, Clinical Staging, and Tumour Marker Expression Rates—A Comprehensive Statistical Analysis

  • Klaus-Peter Dieckmann,
  • Hendrik Isbarn,
  • Francesca Grobelny,
  • Cansu Dumlupinar,
  • Julia Utschig,
  • Christian Wülfing,
  • Uwe Pichlmeier and
  • Gazanfer Belge

5 November 2022

The role of primary tumour size (TS) in the clinical course of testicular tumours is incompletely understood. We retrospectively evaluated 641 consecutive patients with testicular neoplasms with regard to TS, histology, clinical stage (CS), serum tum...