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Keywords = chlorosulfonation-amidation

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Short Note
2-Methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl)ethenyl-3,4-dihydroquinazolin-3-yl]benzene-1-sulfonamide
by Hayun, Muhammad Hanafi, Arry Yanuar and Sumi Hudiyono
Molbank 2012, 2012(3), M765; https://doi.org/10.3390/M765 - 18 Jul 2012
Cited by 1 | Viewed by 5000
Abstract
The title compound, 2-methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl) ethenyl-3, 4-dihydroquinazolin-3-yl] benzene-1-sulfonamide 2 has been synthesized by the reaction of 3-(4-methoxyphenyl)-2-styryl-4(3H)-quinazolinone 1 with an excess of chlorosulfonic acid, followed by amidation of the sulfonyl chloride product with ammonia gas. The structure of the synthesized [...] Read more.
The title compound, 2-methoxy-5-{4-oxo-2-[(E)-2-(4-sulfamoylphenyl) ethenyl-3, 4-dihydroquinazolin-3-yl] benzene-1-sulfonamide 2 has been synthesized by the reaction of 3-(4-methoxyphenyl)-2-styryl-4(3H)-quinazolinone 1 with an excess of chlorosulfonic acid, followed by amidation of the sulfonyl chloride product with ammonia gas. The structure of the synthesized compound was confirmed on the basis of IR, 1H-NMR, 13C-NMR and mass spectral data. Full article
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