Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = carbocyclic hydantoins

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
7 pages, 1904 KiB  
Short Note
1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione
by Vasiliki Pardali, Sotirios Katsamakas, Erofili Giannakopoulou and Grigoris Zoidis
Molbank 2021, 2021(2), M1228; https://doi.org/10.3390/M1228 - 4 Jun 2021
Cited by 1 | Viewed by 3767
Abstract
A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification. Therefore, the proposed method, with an overall yield of 60%, offers a facile pathway to the synthesis of [...] Read more.
A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification. Therefore, the proposed method, with an overall yield of 60%, offers a facile pathway to the synthesis of N-1 monosubstituted spiro carbocyclic imidazolidine-2,4-diones (hydantoins), which constitute a privileged class of heterocyclic scaffolds with pharmacological interest. Full article
Show Figures

Graphical abstract

Back to TopTop