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Keywords = SMMCI syndrome

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14 pages, 4785 KB  
Case Report
Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome
by Katarzyna Cieślińska, Karolina Karbowska, Katarzyna Zaborowicz and Barbara Biedziak
Children 2026, 13(1), 11; https://doi.org/10.3390/children13010011 - 20 Dec 2025
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Abstract
Solitary Median Maxillary Central Incisor Syndrome is unique congenital developmental defect affecting midline structures of the head and the body. The prevalent symptom is a solitary median incisor of the maxilla in primary and secondary dentition, which is positioned exactly in the midline [...] Read more.
Solitary Median Maxillary Central Incisor Syndrome is unique congenital developmental defect affecting midline structures of the head and the body. The prevalent symptom is a solitary median incisor of the maxilla in primary and secondary dentition, which is positioned exactly in the midline of the alveolus. Other abnormalities that are characteristic of the syndrome include holoprosencephaly, nasal cavity anomalies, cleft palate–lip, hypotelorism, and microcephaly. It is estimated to occur in 1:50,000 live births, with female gender predilection. The cause of the syndrome is related to midline defects in the migration and connection of the prechordal mesoderm between the 35th and 38th days post-conception. Early diagnosis of SMMCI is important for practicing orthodontists, as it may be a symptom of other developmental abnormalities. The aim of this study is to report a case of SMMCI syndrome in a patient treated in the Department of Orthodontics and Facial Malformation of the University of Medical Sciences in Poznan. Full article
(This article belongs to the Special Issue Pediatric Dental Restoration: Innovations in Treatment and Materials)
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