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5 Results Found

  • Review
  • Open Access
1 Citations
3,180 Views
12 Pages

14 January 2025

After four decades of intensive research, traditional vaccination strategies for HIV-1 remain ineffective due to HIV-1′s extraordinary genetic diversity and complex immune evasion mechanisms. Cytomegaloviruses (CMV) have emerged as a novel type...

  • Review
  • Open Access
21 Citations
8,158 Views
19 Pages

27 March 2014

The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout...

  • Article
  • Open Access
3 Citations
2,423 Views
25 Pages

Mathematical Modeling of Rhesus Cytomegalovirus Transplacental Transmission in Seronegative Rhesus Macaques

  • Yishu Gong,
  • Matilda Moström,
  • Claire Otero,
  • Sarah Valencia,
  • Alice F. Tarantal,
  • Amitinder Kaur,
  • Sallie R. Permar and
  • Cliburn Chan

1 October 2023

Approximately 0.7% of infants are born with congenital cytomegalovirus (CMV), making it the most common congenital infection. About 1 in 5 congenitally infected babies will suffer long-term sequelae, including sensorineural deafness, intellectual dis...

  • Article
  • Open Access
4 Citations
7,238 Views
22 Pages

Cognitive Effects of Toxoplasma and CMV Infections: A Cross-Sectional Study of 557 Young Adults Considering Modulation by Sex and Rh Factor

  • Jaroslav Flegr,
  • Veronika Chvátalová,
  • Lenka Příplatová,
  • Petr Tureček,
  • Petr Kodym,
  • Blanka Šebánková and
  • Šárka Kaňková

One-third of humanity harbors a lifelong infection with Toxoplasma gondii, and probably about 80% are infected with human cytomegalovirus (CMV). This study aims to delineate the associations between toxoplasmosis and cognitive abilities and compare t...

  • Review
  • Open Access
12 Citations
5,642 Views
17 Pages

Exploring the Potential of Cytomegalovirus-Based Vectors: A Review

  • Janine Zeng,
  • Dabbu Kumar Jaijyan,
  • Shaomin Yang,
  • Shaokai Pei,
  • Qiyi Tang and
  • Hua Zhu

2 October 2023

Viral vectors have emerged as powerful tools for delivering and expressing foreign genes, playing a pivotal role in gene therapy. Among these vectors, cytomegalovirus (CMV) stands out as a promising viral vector due to its distinctive attributes incl...