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Keywords = N-tosylpropargyl amines

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13 pages, 2278 KB  
Article
Gold(III)-Catalyzed Propargylic Substitution Reaction Followed by Cycloisomerization for Synthesis of Poly-Substituted Furans from N-Tosylpropargyl Amines with 1,3-Dicarbonyl Compounds
by Nobuyoshi Morita, Shingo Uchida, Hitomi Chiaki, Naho Ishii, Kentaro Tanikawa, Kosaku Tanaka, Yoshimitsu Hashimoto and Osamu Tamura
Molecules 2024, 29(2), 378; https://doi.org/10.3390/molecules29020378 - 11 Jan 2024
Cited by 2 | Viewed by 2427
Abstract
The treatment of N-tosylpropargyl amines 1 with 1,3-dicarbonyl compounds 2 in the presence of AuBr3 (5 mol%) and AgOTf (15 mol%) afforded poly-substituted furans 3 in good-to-high yields via the gold-catalyzed cleavage of the sp3 carbon–nitrogen bond. Full article
(This article belongs to the Section Organic Chemistry)
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