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Keywords = Jasonia

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22 pages, 1223 KiB  
Review
Jasonia glutinosa (L.) DC.: Back in Our Pantries? A Review of Its Pharmacological Activity and Mechanisms of Action
by Marta Sofía Valero, Carlota Gómez-Rincón, Víctor López and Francisco Les
Int. J. Mol. Sci. 2025, 26(6), 2536; https://doi.org/10.3390/ijms26062536 - 12 Mar 2025
Viewed by 644
Abstract
Jasonia glutinosa (L.) DC., commonly known in Spain as “Rock Tea”, is a medicinal plant native to the Iberian Peninsula, southern France, and Morocco. It has traditionally been used as a digestive, analgesic, antimicrobial, antidepressant, or for respiratory diseases. This narrative review aims [...] Read more.
Jasonia glutinosa (L.) DC., commonly known in Spain as “Rock Tea”, is a medicinal plant native to the Iberian Peninsula, southern France, and Morocco. It has traditionally been used as a digestive, analgesic, antimicrobial, antidepressant, or for respiratory diseases. This narrative review aims to scientifically validate the ethnopharmacological uses of J. glutinosa as a medicinal plant, emphasizing the relationship between its traditional applications, pharmacological activities, and mechanisms of action based on experimental evidence. A comprehensive search was conducted in various electronic databases to gather information on its traditional uses, phytochemical composition, and in vitro, ex vivo, and in vivo studies related to pharmacological properties. The literature review uncovered significant findings regarding the pharmacological and molecular mechanisms of this medicinal plant in various experimental models, particularly highlighting its spasmolytic, anti-inflammatory, and antioxidant properties. Full article
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42 pages, 2840 KiB  
Review
The Genus Chiliadenus: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities
by Lucinda Villaescusa Castillo, Francisco Zaragozá García and Cristina Zaragozá Arnáez
Plants 2025, 14(2), 205; https://doi.org/10.3390/plants14020205 - 13 Jan 2025
Cited by 2 | Viewed by 1542
Abstract
The genus Chiliadenus (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemical composition and pharmacological characteristics. This review compiles [...] Read more.
The genus Chiliadenus (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemical composition and pharmacological characteristics. This review compiles existing knowledge on Chiliadenus species, focusing on their secondary metabolites, such as flavonoids, terpenes, and essential oils, as well as associated biological activities. The findings show that the traditional therapeutic properties of Chiliadenus are well supported by reported pharmacological activities in previous studies, emphasizing the potential of this genus for the development of new therapeutic agents. However, the lack of comparative studies among Chiliadenus species and the scarcity of in vivo studies and clinical trials hinder the full realization of its therapeutic potential. Specifically, comparative studies could be key to identifying species with unique chemical profiles and understanding how variations in secondary metabolite composition may influence their pharmacological activities. This work highlights the urgent need to expand research in these areas to validate the pharmacological properties of Chiliadenus species for their application in modern medicine. Full article
(This article belongs to the Section Phytochemistry)
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13 pages, 1654 KiB  
Article
Jasonia glutinosa (L.) DC., a Traditional Herbal Tea, Exerts Antioxidant and Neuroprotective Properties in Different In Vitro and In Vivo Systems
by Francisco Les, Marta Sofía Valero, Cristina Moliner, David Weinkove, Víctor López and Carlota Gómez-Rincón
Biology 2021, 10(5), 443; https://doi.org/10.3390/biology10050443 - 18 May 2021
Cited by 8 | Viewed by 3498
Abstract
In traditional medicine, Jasonia glutinosa (L.) DC or rock tea (RT) has been mainly used to treat digestive and respiratory pathologies but also as an antimicrobial or an antidepressant herbal remedy. An ethanolic extract of RT has been demonstrated to have antioxidant and [...] Read more.
In traditional medicine, Jasonia glutinosa (L.) DC or rock tea (RT) has been mainly used to treat digestive and respiratory pathologies but also as an antimicrobial or an antidepressant herbal remedy. An ethanolic extract of RT has been demonstrated to have antioxidant and anti-inflammatory effects, which may be explained by its phytochemical profile, rich in polyphenols and pigments. The aim of this study is to investigate the neuroprotective potential of RT. For this purpose, the ethanolic extract of RT is assayed in Caenorhabditis elegans (C. elegans) as an in vivo model, and through in vitro assays using monoamine oxidase A, tyrosinase and acetylcholinesterase as enzymes. The RT extract reduces juglone-induced oxidative stress in worms and increases the lifespan and prevents paralysis of C. elegans CL4176, a model of Alzheimer’s disease; the extract is also able to inhibit enzymes such as acetylcholinesterase, monoamine oxidase A and tyrosinase in vitro. Together these results demonstrate that Jasonia glutinosa is a good candidate with antioxidant and neuroprotective potential for the development of new products with pharmaceutical interests. Full article
(This article belongs to the Special Issue Bioactivity of Medicinal Plants and Extracts)
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