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Keywords = GBDE

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18 pages, 1179 KB  
Article
Secure Data Management Life Cycle for Government Big-Data Ecosystem: Design and Development Perspective
by Reeba Zahid, Ayesha Altaf, Tauqir Ahmad, Faiza Iqbal, Yini Airet Miró Vera, Miguel Angel López Flores and Imran Ashraf
Systems 2023, 11(8), 380; https://doi.org/10.3390/systems11080380 - 25 Jul 2023
Cited by 18 | Viewed by 8656
Abstract
The rapid generation of data from various sources by the public sector, private corporations, business associations, and local communities is referred to as big data. This large and complex dataset is often regarded as the ‘new oil’ by public administrations (PAs), and data-driven [...] Read more.
The rapid generation of data from various sources by the public sector, private corporations, business associations, and local communities is referred to as big data. This large and complex dataset is often regarded as the ‘new oil’ by public administrations (PAs), and data-driven approaches are employed to transform it into valuable insights that can improve governance, transparency, digital services, and public engagement. The government’s big-data ecosystem (GBDE) is a result of this initiative. Effective data management is the first step towards large-scale data analysis, which yields insights that benefit your work and your customers. However, managing big data throughout its life cycle is a daunting challenge for public agencies. Despite its widespread use, big data management is still a significant obstacle. To address this issue, this study proposes a hybrid approach to secure the data management life cycle for GBDE. Specifically, we use a combination of the ECC algorithm with AES 128 BITS encryption to ensure that the data remain confidential and secure. We identified and analyzed various data life cycle models through a systematic literature review to create a data management life cycle for data-driven governments. This approach enhances the security and privacy of data management and addresses the challenges faced by public agencies. Full article
(This article belongs to the Special Issue AI-Powered Data Management and Analysis for Cyber-Physical-Systems)
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24 pages, 10058 KB  
Review
CRLF1 and CLCF1 in Development, Health and Disease
by Laura Crisponi, Insa Buers and Frank Rutsch
Int. J. Mol. Sci. 2022, 23(2), 992; https://doi.org/10.3390/ijms23020992 - 17 Jan 2022
Cited by 43 | Viewed by 8269
Abstract
Cytokines and their receptors have a vital function in regulating various processes such as immune function, inflammation, haematopoiesis, cell growth and differentiation. The interaction between a cytokine and its specific receptor triggers intracellular signalling cascades that lead to altered gene expression in the [...] Read more.
Cytokines and their receptors have a vital function in regulating various processes such as immune function, inflammation, haematopoiesis, cell growth and differentiation. The interaction between a cytokine and its specific receptor triggers intracellular signalling cascades that lead to altered gene expression in the target cell and consequent changes in its proliferation, differentiation, or activation. In this review, we highlight the role of the soluble type I cytokine receptor CRLF1 (cytokine receptor-like factor-1) and the Interleukin (IL)-6 cytokine CLCF1 (cardiotrophin-like cytokine factor 1) during development in physiological and pathological conditions with particular emphasis on Crisponi/cold-induced sweating syndrome (CS/CISS) and discuss new insights, challenges and possibilities arising from recent studies. Full article
(This article belongs to the Special Issue Cytokine Receptors In Development, Homeostasis & Disease)
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