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Keywords = Chamaenerion latifolium

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26 pages, 1958 KiB  
Review
Phytochemical Insights and Therapeutic Potential of Chamaenerion angustifolium and Chamaenerion latifolium
by Akmaral Kozhantayeva, Zhanar Iskakova, Manshuk Ibrayeva, Ardak Sapiyeva, Moldir Arkharbekova and Yerbolat Tashenov
Molecules 2025, 30(5), 1186; https://doi.org/10.3390/molecules30051186 - 6 Mar 2025
Cited by 2 | Viewed by 1106
Abstract
The Chamaenerion genus, particularly Chamaenerion angustifolium and Chamaenerion latifolium, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides [...] Read more.
The Chamaenerion genus, particularly Chamaenerion angustifolium and Chamaenerion latifolium, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides a comprehensive analysis of their phytochemical constituents, with an emphasis on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally, this review evaluates the biological activities of Chamaenerion species in relation to their chemical composition, while also considering the limitations of current studies, such as the lack of in vivo or clinical trials. The literature for this review was sourced from scientific databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to 2024. Future studies should focus on optimizing extraction methods, elucidating synergistic bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety. Full article
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17 pages, 3014 KiB  
Article
Phytochemical Profiling, Antioxidant and Antimicrobial Potentials of Ethanol and Ethyl Acetate Extracts of Chamaenerion latifolium L.
by Akmaral Kozhantayeva, Nurgul Tursynova, Ainagul Kolpek, Yelaman Aibuldinov, Arailym Tursynova, Togzhan Mashan, Zhazira Mukazhanova, Manshuk Ibrayeva, Aizhan Zeinuldina, Aisha Nurlybayeva, Zhanar Iskakova and Yerbolat Tashenov
Pharmaceuticals 2024, 17(8), 996; https://doi.org/10.3390/ph17080996 - 27 Jul 2024
Cited by 4 | Viewed by 2036
Abstract
The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from Chamaenerion latifolium L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.48 ± 3.44 mg GAE/g DE) and flavonoid content [...] Read more.
The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from Chamaenerion latifolium L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.48 ± 3.44 mg GAE/g DE) and flavonoid content (24.18 ± 1.06 mg QE/g DE) compared to ChL-EtOAc. HPLC-UV-ESI/MS identified key phenolic acids and flavonoids, including gallic acid, chlorogenic acid, and quercetin 3-glucoside. FT-IR analysis confirmed the presence of characteristic functional groups. Antioxidant assays revealed strong DPPH scavenging and FRAP activities, with ChL-EtOH showing superior results (IC50 = 21.31 ± 0.65 μg/mL and 18.13 ± 0.15 μg/mL, respectively). Additionally, ChL-EtOH displayed notable antimicrobial efficacy against Gram-positive and Gram-negative bacteria, as well as the fungal strain Candida albicans. These findings suggest that ethanol extraction is more efficient for isolating bioactive compounds from ChL, underscoring its potential for pharmaceutical and nutraceutical applications. Full article
(This article belongs to the Section Natural Products)
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