Search Results (12)

Background: Since 1974, Essential Programme on Immunisation managers from ten Central African countries meet yearly with partners to review progress made and share experiences and lessons learned from the implementation of immunization programmes. The 2024 meeting occurred in Kinshasa, Democratic Republic of Congo, in September 2024. This conference report summarizes the key takeaways from discussions on using immunization data for decision-making, the implementation of the Big Catch-Up (BCU) initiative to reduce the burden of zero-dose children, and progress and challenges in introducing selected new vaccines. Conference Takeaways: Inaccurate administrative data on routine immunization observed in most countries, compared to WHO/UNICEF Estimates of National Immunization Coverage and national survey estimates, affect timely decisions to improve the Expanded Programme on Immunization (EPI) performance. Five countries in Central Africa are among the priority countries of the BCU initiative but, as of the end of August 2024, are yet to formally start its implementation. Cameroon and Central African Republic introduced the malaria vaccine in January 2024 and August 2024, respectively, while the Democratic Republic of Congo, Chad, and Burundi have planned to do so by 2025. Conclusions and Recommendations: Meeting participants put forward several recommendations for countries and immunization partners, including but not limited to (i) investing more in routine immunization data quality assurance to better use data to inform decisions, (ii) accelerating the implementation of the BCU initiative to close the immunity gap resulting from routine immunization disruptions due to the COVID-19 pandemic, (iii) updating malaria vaccine introduction plans to invest more in demand generation and community engagement, and (iv) learning from Cameroon’s experience in tackling hesitancy to human papilloma virus vaccine. It is critical to set up an appropriate mechanism for monitoring the implementation of these recommendations. Full article

Background: Gastric diseases caused, in particular, by Campylobacter, non-typhoidal Salmonella, and Shigella resulting from food and/or water problems, are a disproportionately distributed burden in developing countries in Central Africa. The aim of this work was to compile a list of studies establishing the prevalence of the involvement of these bacterial genera in diarrheal syndromes in Central Africa from 1998 to 2022. Methods: The Preferred Reporting Articles for Systemic Reviews and Meta-Analyses, six (6) database (Pubmed, Google Scholar, Semantic Scholar, Freefullpdf, and Scinapse) were perused for research on the role of Campylobacter, Salmonella and Shigella diarrheal infections in humans and animals, in 9 country of Central Africa over from 1998 to 2022. Results: Seventeen articles were selected, including 16 on humans and one on animals. These data were recorded in 6 of the 9 countries of Central Africa, including Gabon (5), Angola (3), Cameroon (3), the Democratic Republic of Congo (3), Chad (2), and the Central African Republic (1). Mono-infections with Salmonella spp. were the most predominant (55.56%, n = 5/9), followed by an equal proportion of Campylobacter spp. and Shigella spp. with 44.44% (4/9), respectively and, co-infections with Campylobacter/Salmonella spp. and Salmonella/Shigella spp. with a prevalence of 11.11% (1/9) respectively. The most used diagnostic tool was conventional culture (82.35%) against 17.65% for PCR or real-time PCR. Conclusion: Despite the paucity of recorded data on the prevalence of diarrheal infections due to Campylobacter in this sub-region, it is crucial that scientific studies focus on the diagnosis and monitoring of this zoonotic bacterium. Also, improved diagnosis will necessarily involve the integration of molecular tools in the diagnosis of these diarrheic syndromes in both humans and animals. Full article

On the African continent, South Africa has world-class astronomical facilities for advanced radio astronomy research. With the advent of the Square Kilometre Array project in South Africa (SA SKA), six countries in Africa (SA SKA partner countries) have joined South Africa to contribute towards the African Very Long Baseline Interferometry (VLBI) Network (AVN). Each of the AVN countries aims to construct a single-dish radio telescope that will be part of the AVN, the European VLBI Network, and the global VLBI network. The SKA and the AVN will enable very high sensitivity VLBI in the southern hemisphere. In the current AVN, there is a gap in the coverage in the central African region. This work analyses the increased scientific impact of having additional antennas in each of the six countries in central Africa, i.e., Cameroon, Gabon, Congo, Equatorial Guinea, Chad, and the Central African Republic. A number of economic human capital impacts of having a radio interferometer in central Africa are also discussed. This work also discusses the recent progress on the AVN project and shares a few lessons from some past successes in ground stations retrofitting. Full article

The fish diversity of the Adamawa lakes is among the most undocumented in Northern Cameroon. Faced with this lack of knowledge, an inventory of ichthyofauna and habitats characterization was conducted in nine lakes. Seven lakes (Assom, Gegouba, Massote, Mbalang, Ngaoundaba, Piou and Tizong) are located in the Sanaga Basin and two (Bini and Dang) are located in the Lake Chad Basin. In order to assess the composition and variation in fish assemblage, eight sampling campaigns were carried out seasonally between 2017 and 2018; they revealed 26 species of fish distributed in 6 orders, 9 families and 16 genera. Communities in Lakes Assom (13 species) and Bini (9 species) were the most diverse. Omnivorous (42.3%) and spawners in open water or on substrates of sand, gravel, rock or plants (69.2%) were the most represented. Nonmetric multidimensional scaling, analysis of similarities (ANOSIM), and similarity percentage analysis (SIMPER) revealed that fish species composition differed significantly among lakes. Canonical correspondence analysis (CCA) identified temperature, pH, TDS, and conductivity as variables explaining the most variation in fish species. The presence of four endemic species in the Sanaga Basin in lakes Assom, Gegouba, Massote and Piou, shows that these lakes stand out as hotspots for conservation due to the uniqueness of their ichthyofauna. Full article

Since July 2009, when the popular founder of Boko Haram, Mohammed Yusuf, was extrajudicially killed by the police, the group has become radicalised. Boko Haram started by terrorising the country, particularly the northeastern zone, which extends to Cameroon, Niger, and Lake Chad. Several works on the group, mostly by foreign commentators and scholars, have mainly attributed its rise to political and economic factors. Many of those works have not also recognised the metamorphosis from terrorism to insurgency, wherein the group is now replacing the secular status of Nigeria’s configuration with a monolithic Islamic caliphal rule in the swathes of land that it has captured. Even though the Nigerian government has adopted the factors canvassed by those scholars and also denies the group an ideological anchorage, I argue that Boko Haram’s ideological scaffolding is hinged on ultra-jihadi Salafism. Relying on qualitative sources, I employ a historical and interpretive framework in explicating the origin of Boko Haram and in content analysing President Muhammad Buhari’s 2015 inaugural speech, which denies the group of any ideological leaning on Islam. I then contend that such a denial has made counter-insurgency measures of the government counter-productive, as efforts at meeting political and economic factors are difficult to achieve in the present circumstance. I, therefore, recommend counter-insurgency measures, which include, amongst others, Western education, Islamic de-radicalisation processes, and counter-insurgency narratives, as well as ideas to cut off the recruitment of youth into the group and military engagement, as both short- and long-term strategies. Full article

Precise agricultural predictions of climate change effects on crop water productivity are essential to ensure food security and alleviate water scarcity. In this regard, the present study provides an overview of the future impacts of climate change on the irrigation of agricultural products such as rice, millet, maize, cassava, sorghum, and sugar cane. These crops are some of the most-consumed foodstuffs in countries of the Niger River basin. This study is realized throughout 2020 to 2080, and three Global Climate Models (GCMs) (CSIRO, MIROC5, and ECHAM. MPI-ESM-LR) have been used. The GCMs data have been provided by the IPCC5 database. The irrigation water requirement for each crop was calculated using Smith’s CROPWAT approach. The Penman–Monteith equation recommended by the FAO was used to calculate the potential evapotranspiration. The inter-annual results of the IWR, according to the set of models selected, illustrate that the largest quantities of water used for irrigation are generally observed between January and March, and the lowest quantities are the most often seen between July and September. The majority of models also illustrate a peak in the IWR between March and April. Sorghum and millet are the crops consuming the least amount of water for irrigation; followed by cassava, then rice and corn, and finally sugar cane. The most significant IWRs, which have been predicted, will be between 16.3 mm/day (MIROC5 model, RCP 4.5) and 45.9 mm/day (CSIRO model, RCP 4.5), particularly in Mali, Niger, Algeria, and rarely in Burkina-Faso (CSIRO model, RCP4.5 and 8.5). The lowest IWRs predicted by the models will be from 1.29 mm/day (MIROC5 model, RCP 4.5) to 33.4 mm/day (CSIRO model, RCP 4.5); they will be observed according to the models in Guinea, southern Mali, Ivory Coast, center and southern Nigeria, and Cameroon. However, models predict sugarcane to be the plant with the highest IWR, between 0.25 mm/day (Benin in 2020–2040) and 25.66 mm/day (Chad in 2060–2080). According to the models’ predictions, millet is the crop with the most IWR, between 0.20 mm/day (Benin from 2020 to 2060) and 19.37 mm/day (Chad in 2060–2080). With the results of this study, the countries belonging to the Niger River basin can put in place robust policies in the water resources and agriculture sectors, thus ensuring food security and high-quality production of staple crops, and avoiding water scarcity while facing the negative impacts of climate change. Full article

The HIV/AIDS incidence rates have decreased in African countries although the rates are still high in Sub-Saharan Africa. Our study aimed to examine the long-term trend of the overall HIV/AIDS incidence rates in four countries of the central region of Africa, using data from the Global Burden of Diseases (GBD) 2019 study. The Age–Period–Cohort statistical model analysis was used to measure the trends of HIV/AIDS incidence rates in each of the four countries. HIV/AIDS incidence rates decreased slowly in Cameroon (CAM), Chad, and Central African Republic (CAR), but considerably in the Democratic Republic of the Congo (DRC) from 1990–2019. HIV/AIDS incidence rates in the four countries were at their peaks in the age group of 25–29 years. According to the age relative risks, individuals aged between 15 and 49 years old are at high risk of HIV/AIDS incidence in the four countries. The period and cohort relative risks have decreased in all four countries. Although CAM recorded an increase of 59.6% in the period relative risks (RRs) between 1990 and 1999, HIV/AIDS incidence has decreased dramatically in all four countries, especially after 2000. The decrease of the period RRs (relative risk) by nearly 20.6-folds and the decrease of the cohort RRs from 147.65 to almost 0.0034 in the DRC made it the country with the most significant decrease of the period and cohort RRs compared to the rest. HIV/AIDS incidence rates are decreasing in each of the four countries. Our study findings could provide solid ground for policymakers to promptly decrease HIV/AIDS incidence by strengthening the prevention policies to eliminate the public health threat of HIV/AIDS by 2030 as one of the targets of the Sustainable Development Goals (SDGs). Full article

Guinea worm disease (GWD) is a neglected tropical disease that was targeted for eradication several decades ago because of its limited geographical distribution, predictable seasonality, straightforward diagnosis, and exclusive infection of humans. However, a growing body of evidence challenges this last attribute and suggests that GWD can affect both humans and animal populations. The One Health approach emphasizes the relatedness of human, animal, and environmental health. We reviewed epidemiological evidence that could support the utility of a One Health approach for GWD control in the six countries that have reported human GWD cases since 2015—Angola, Cameroon, Chad, Ethiopia, Mali, and South Sudan. Human GWD cases have dramatically declined, but recent years have seen a gradual increase in human case counts, cases in new geographies, and a rapidly growing number of animal infections. Taken together, these suggest a need for an adjusted approach for eradicating GWD using a framework rooted in One Health, dedicated to improving disease surveillance and in animals; pinpointing the dominant routes of infection in animals; elucidating the disease burden in animals; determining transmission risk factors among animals and from animals to humans; and identifying practical ways to foster horizontal and multidisciplinary approaches. Full article

Although herpes simplex virus-2 (HSV-2) infection is a known cofactor for HIV transmission in Central Africa, its role in HIV disease progression is unclear. The aim of this study was to examine the potential link between HSV-2 infection and HIV disease progression, in addition to identifying the presence of genes conferring HIV antiretroviral resistance mutations. This was a cross-sectional study involving 302 HIV-infected adults in Central Africa with virological failure (viral load >1000 copies/mL) on first-line antiretroviral therapy from four different countries. The seroprevalence of HSV-2 was 32% (96/302). Amongst the HIV-infected individuals who were HSV-2 seropositive, the mean HIV viral load and CD4 count were 4.82 ± 0.83 log copies/mL and 243 ± 144 cells/microliter, respectively. Among the HIV-infected individuals who were HSV-2-seronegative, the mean HIV viral load and CD4 count were 3.48 ± 0.44 log copies/mL and 646 ± 212 cells/microliter, respectively (p < 0.001). There was a statistically significant relationship (p < 0.001) between HSV-2 seropositivity and the presence of resistance mutations to antiretrovirals (ARV), non-nucleoside reverse transcriptase inhibitors (NNRTI), and nucleoside reverse transcriptase inhibitors (NRTI) with odds ratios of 9.7, 10, and 11.9, respectively. There was no link between HSV-2 serostatus and protease inhibitor (PI) resistance mutations. There was a substantial accumulation of resistance mutations in HSV-2-seropositive compared to -seronegative patients. These findings support the link between HIV disease progression and HSV-2 infection. An association was observed between the presence of NNRTI and NRTI resistance mutations and HSV-2 seropositivity. Full article

The Lake Chad Basin has for a very long period supported the livelihoods of millions of peoples from the different countries that share this transboundary water resource. Its shrinking over the decades has meant that many of those who depend on it for livelihoods would have to adjust to the changing resource environment of this lake basin. This study sets out to examine the seasonal migration of people in search of water, pasture, fuelwood and cultivable land, and how this movement affects access and use of basin resources. The study made use of survey data obtained from 220 household heads on the Cameroon side of the Lake Chad basin, and secondary data from Cameroon ministries in charge of agriculture, the environment, and that of livestock. Our findings show that while fishing and livestock rearing continue to feature among the oldest determinants of population movements in the Lake Chad basin, increasingly the search for new farming opportunities made available by a shrinking lake and the political instability emanating from Nigeria are also becoming an important determinant. The increasing population in the lake region is compounding pressures created by a shrinking lake on access to water, fuelwood, pasture, and farmland. While there is potential to develop and benefit from the agricultural possibilities emerging from a shrinking lake, the impacts of poor agricultural resource management (especially land degradation, loss of agricultural biodiversity, and poor water management) may hamper the sustainable practice of agriculture if proper efforts are not made to address them. This study contributes to the scientific understanding of the changing nature of environmental resources in Africa. It specifically contributes to understanding the exacerbating threats to the sustainability of natural resources (water, agricultural and grazing land) caused by environmental changes, diversification of rural actors (fishers, farmers, breeders), weak resource management, and since 2013, by an armed conflict. Full article

Field assessment plays a key role in the evaluation of the energy access modalities and of the socio-economic features that may influence the beneficiaries’ choices and preferences in the adoption and use of an energy technology. This work presents the findings of a survey conducted during the implementation of a cooperation project in the Logone Valley (Chad/Cameroon). After an initial period of promotion of an improved cookstove (ICS), a survey was conducted that was aimed at identifying different beneficiary groups, matching their preferences and cooking habits to the technology proposed, in order to best tailor the scaling-up strategy. In-depth analysis of the data gathered identified two household-user behaviors and the relative influencing features: in the urban area, the increased adoption rates confirmed the appropriateness of the technology proposed and its sustainability, whereas in the rural area, ICS use was not perceived by the final users as advantageous and lower adoption rates were observed. Thus, due to the outcome of the survey, the project action was re-oriented in order to achieve a higher impact on the territory and on the population. Full article

Unsafe drinking water is one of the main concerns in developing countries. In order to deal with this problem, a cooperation project was set up by the ACRA Foundation in the Logone valley (Chad-Cameroon). Water supplies were sampled throughout the villages of this area mostly from boreholes, open wells, rivers and lakes as well as some piped waters. The samples were analysed for their physical-chemical and microbiological quality in order to identify the contamination problems and suggest appropriate solutions. Results of the assessment confirmed that in the studied area there are several parameters of health and aesthetic concern. Elevated lead levels were detected both in aquifers and in surface waters, confirming that further investigations of the occurrence of lead contamination in the Logone valley are warranted. In addition, many groundwater sources are negatively impacted by parameters of aesthetic concern, such as turbidity, iron and manganese. Even though they do not affect human health, elevated levels of these parameters cause consumers to abandon improved water supplies, often in favour of surface water sources that are microbiologically contaminated. The use of alternative sources, improvement of water supply structures and water treatment are possible solutions to improve the quality of drinking water in the Logone valley. Full article