Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (3)

Search Parameters:
Keywords = Cespitularia sp.

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
12 pages, 1292 KiB  
Article
New Verticillene Diterpenoids, Eudesmane Sesquiterpenoids, and Hydroperoxysteroids from the Further Chemical Investigation of a Taiwanese Soft Coral Cespitularia sp.
by Chung-Wei Fu, You-Cheng Lin, Shu-Fen Chiou, Shu-Li Chen, Chi-Chien Lin, Hui-Chun Wang, Chang-Feng Dai and Jyh-Horng Sheu
Molecules 2023, 28(4), 1521; https://doi.org/10.3390/molecules28041521 - 4 Feb 2023
Cited by 3 | Viewed by 2574
Abstract
An investigation of the chemical composition of a Formosan soft coral Cespitularia sp. led to the discovery of one new verticillene-type diterpenoid, cespitulactam M (1); one new eudesmane sesquiterpenoid, cespilamide F (2); and three new hydroperoxysteroids (3 [...] Read more.
An investigation of the chemical composition of a Formosan soft coral Cespitularia sp. led to the discovery of one new verticillene-type diterpenoid, cespitulactam M (1); one new eudesmane sesquiterpenoid, cespilamide F (2); and three new hydroperoxysteroids (35) along with twelve known analogous metabolites (617). In addition, one new derivative, cespitulactam M-6,2′-diacetate (1a), was prepared from compound 1. The structures were determined by detailed spectroscopic analyses, particularly HRESIMS and NMR techniques. Moreover, the in vitro cytotoxicity, anti-inflammatory, and antibacterial activity of 117 and 1a were evaluated. Full article
Show Figures

Graphical abstract

26 pages, 4997 KiB  
Article
Bioactive Diterpenes, Norditerpenes, and Sesquiterpenes from a Formosan Soft Coral Cespitularia sp.
by You-Cheng Lin, Chi-Chien Lin, Yi-Chia Chu, Chung-Wei Fu and Jyh-Horng Sheu
Pharmaceuticals 2021, 14(12), 1252; https://doi.org/10.3390/ph14121252 - 1 Dec 2021
Cited by 9 | Viewed by 3246
Abstract
Chemical investigation of the soft coral Cespitularia sp. led to the discovery of twelve new verticillane-type diterpenes and norditerpenes: cespitulins H–O (18), one cyclic diterpenoidal amide cespitulactam L (9), norditerpenes cespitulin P (10), cespitulins Q [...] Read more.
Chemical investigation of the soft coral Cespitularia sp. led to the discovery of twelve new verticillane-type diterpenes and norditerpenes: cespitulins H–O (18), one cyclic diterpenoidal amide cespitulactam L (9), norditerpenes cespitulin P (10), cespitulins Q and R (11 and 12), four new sesquiterpenes: cespilins A–C (1315) and cespitulolide (16), along with twelve known metabolites. The structures of these metabolites were established by extensive spectroscopic analyses, including 2D NMR experiments. Anti-inflammatory effects of the isolated compounds were studied by evaluating the suppression of pro-inflammatory protein tumor necrosis factor-α (TNF-α) and nitric oxide (NO) overproduction, and the inhibition of the gene expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), in lipopolysaccharide-induced dendritic cells. A number of these metabolites were found to exhibit promising anti-inflammatory activities. Full article
(This article belongs to the Special Issue Chemistry and Biomedical Potential of Marine Natural Products)
Show Figures

Figure 1

8 pages, 361 KiB  
Article
Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
by Prodip K. Roy, Wilmar Maarisit, Michael C. Roy, Junsei Taira and Katsuhiro Ueda
Mar. Drugs 2012, 10(12), 2741-2748; https://doi.org/10.3390/md10122741 - 30 Nov 2012
Cited by 19 | Viewed by 7220
Abstract
Five new diterpenoids 15 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related [...] Read more.
Five new diterpenoids 15 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonolide (6) was cytotoxic against HCT 116 cells (IC50 5.85 μM), while these new diterpenoids 15 were much less active (IC50 28.2–91.4 μM). Full article
Show Figures

Figure 1

Back to TopTop