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Keywords = Aster tripolium L.

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13 pages, 1427 KiB  
Article
Structural Elucidation and Antiviral Properties of Pannosides from the Halophyte Aster tripolium L.
by Jaeyoun Lee, Jae-Hyoung Song, Seo-Hyeon Mun, Hyun-Jeong Ko, Soohyun Um and Seung Hyun Kim
Mar. Drugs 2024, 22(12), 524; https://doi.org/10.3390/md22120524 - 21 Nov 2024
Viewed by 1330
Abstract
Four previously undescribed pentacyclic triterpenoid saponins, pannosides F–I (14), were isolated from the halophyte Aster tripolium L. (Tripolium pannonicum), and their chemical structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry. Comprehensive structural analysis [...] Read more.
Four previously undescribed pentacyclic triterpenoid saponins, pannosides F–I (14), were isolated from the halophyte Aster tripolium L. (Tripolium pannonicum), and their chemical structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry. Comprehensive structural analysis revealed the presence of distinct aglycone and glycosidic moieties, along with complex acylation patterns. The acyl chains of pannosides, 3-hydroxybutyrate (3-HB) residues, were derivatized with (S)- and (R)- phenylglycine methyl ester to resolve the absolute configurations of the chiral centers in 3-HB. Then, the acyl chain-containing saponins, pannosides were evaluated for their antiviral activities against enterovirus A71 (EV71), coxsackievirus B3 (CVB3), and rhinovirus 1B (HRV1B). Pannosides exhibited antiviral activities against HRV1B, EV71, and CVB3. These findings suggest that saponins from A. tripolium exhibit potential antiviral activities and could be further explored for their therapeutic applications. Full article
(This article belongs to the Special Issue Bioactive Specialized Metabolites from Marine Plants)
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19 pages, 2130 KiB  
Article
Harnessing the Value of Tripolium pannonicum and Crithmum maritimum Halophyte Biomass through Integrated Green Biorefinery
by Laura Sini Sofia Hulkko, Tanmay Chaturvedi, Luísa Custódio and Mette Hedegaard Thomsen
Mar. Drugs 2023, 21(7), 380; https://doi.org/10.3390/md21070380 - 27 Jun 2023
Cited by 6 | Viewed by 2276
Abstract
Bioactive extracts are often the target fractions in bioprospecting, and halophyte plants could provide a potential source of feedstock for high-value applications as a part of integrated biorefineries. Tripolium pannonicum (Jacq.) Dobrocz. (sea aster) and Crithmum maritimum L. (sea fennel) are edible plants [...] Read more.
Bioactive extracts are often the target fractions in bioprospecting, and halophyte plants could provide a potential source of feedstock for high-value applications as a part of integrated biorefineries. Tripolium pannonicum (Jacq.) Dobrocz. (sea aster) and Crithmum maritimum L. (sea fennel) are edible plants suggested for biosaline halophyte-based agriculture. After food production and harvesting of fresh leaves for food, the inedible plant fractions could be utilized to produce extracts rich in bioactive phytochemicals to maximize feedstock application and increase the economic feasibility of biomass processing to bioenergy. This study analyzed fresh juice and extracts from screw-pressed sea aster and sea fennel for their different phenolic compounds and pigment concentrations. Antioxidant and enzyme inhibition activities were also tested in vitro. Extracts from sea aster and sea fennel had phenolic contents up to 45.2 mgGAE/gDM and 64.7 mgGAE/gDM, respectively, and exhibited >70% antioxidant activity in several assays. Ethanol extracts also showed >70% inhibition activity against acetylcholinesterase and >50% inhibition of tyrosinase and α-glucosidase. Therefore, these species can be seen as potential feedstocks for further investigations. Full article
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