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Keywords = Arcangelisia gusanlung

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Article
Protoberberine Isoquinoline Alkaloids from Arcangelisia gusanlung
by Ling-Ling Yu, Rong-Tao Li, Yuan-Bao Ai, Wei Liu, Zhang-Shuang Deng and Zhong-Mei Zou
Molecules 2014, 19(9), 13332-13341; https://doi.org/10.3390/molecules190913332 - 29 Aug 2014
Cited by 34 | Viewed by 9302
Abstract
HPLC-DAD-directed isolation and purification of the methanol extract of stems of Arcangelisia gusanlung H. S. Lo. led to the isolation of a new protoberberine alkaloid, gusanlung E (1), along with fourteen known derivatives 215, seven [...] Read more.
HPLC-DAD-directed isolation and purification of the methanol extract of stems of Arcangelisia gusanlung H. S. Lo. led to the isolation of a new protoberberine alkaloid, gusanlung E (1), along with fourteen known derivatives 215, seven of which were obtained from the genus Arcangelisia for the first time. The structures and absolute stereochemistry of these compounds were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR, mass spectrometry, and CD analyses. Gusanlung E (1) expressed weak cytotoxic activity against the SGC 7901 cell line with an IC50 value of 85.1 µM. Full article
(This article belongs to the Section Natural Products Chemistry)
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