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Search Results (3)

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Authors = Stuart P. Atkinson

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15 pages, 8911 KiB  
Article
Low-Cost Automated Vectors and Modular Environmental Sensors for Plant Phenotyping
by Stuart A. Bagley, Jonathan A. Atkinson, Henry Hunt, Michael H. Wilson, Tony P. Pridmore and Darren M. Wells
Sensors 2020, 20(11), 3319; https://doi.org/10.3390/s20113319 - 11 Jun 2020
Cited by 10 | Viewed by 6173
Abstract
High-throughput plant phenotyping in controlled environments (growth chambers and glasshouses) is often delivered via large, expensive installations, leading to limited access and the increased relevance of “affordable phenotyping” solutions. We present two robot vectors for automated plant phenotyping under controlled conditions. Using 3D-printed [...] Read more.
High-throughput plant phenotyping in controlled environments (growth chambers and glasshouses) is often delivered via large, expensive installations, leading to limited access and the increased relevance of “affordable phenotyping” solutions. We present two robot vectors for automated plant phenotyping under controlled conditions. Using 3D-printed components and readily-available hardware and electronic components, these designs are inexpensive, flexible and easily modified to multiple tasks. We present a design for a thermal imaging robot for high-precision time-lapse imaging of canopies and a Plate Imager for high-throughput phenotyping of roots and shoots of plants grown on media plates. Phenotyping in controlled conditions requires multi-position spatial and temporal monitoring of environmental conditions. We also present a low-cost sensor platform for environmental monitoring based on inexpensive sensors, microcontrollers and internet-of-things (IoT) protocols. Full article
(This article belongs to the Special Issue Low-Cost Sensors and Vectors for Plant Phenotyping)
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24 pages, 1206 KiB  
Review
Polymer Therapeutics: Biomarkers and New Approaches for Personalized Cancer Treatment
by Stuart P. Atkinson, Zoraida Andreu and María J. Vicent
J. Pers. Med. 2018, 8(1), 6; https://doi.org/10.3390/jpm8010006 - 23 Jan 2018
Cited by 24 | Viewed by 19279
Abstract
Polymer therapeutics (PTs) provides a potentially exciting approach for the treatment of many diseases by enhancing aqueous solubility and altering drug pharmacokinetics at both the whole organism and subcellular level leading to improved therapeutic outcomes. However, the failure of many polymer-drug conjugates in [...] Read more.
Polymer therapeutics (PTs) provides a potentially exciting approach for the treatment of many diseases by enhancing aqueous solubility and altering drug pharmacokinetics at both the whole organism and subcellular level leading to improved therapeutic outcomes. However, the failure of many polymer-drug conjugates in clinical trials suggests that we may need to stratify patients in order to match each patient to the right PT. In this concise review, we hope to assess potential PT-specific biomarkers for cancer treatment, with a focus on new studies, detection methods, new models and the opportunities this knowledge will bring for the development of novel PT-based anti-cancer strategies. We discuss the various “hurdles” that a given PT faces on its passage from the syringe to the tumor (and beyond), including the passage through the bloodstream, tumor targeting, tumor uptake and the intracellular release of the active agent. However, we also discuss other relevant concepts and new considerations in the field, which we hope will provide new insight into the possible applications of PT-related biomarkers. Full article
(This article belongs to the Special Issue Personalized Nanomedicine)
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33 pages, 481 KiB  
Article
Scenario Archetypes: Converging Rather than Diverging Themes
by Dexter V. L. Hunt, D. Rachel Lombardi, Stuart Atkinson, Austin R. G. Barber, Matthew Barnes, Christopher T. Boyko, Julie Brown, John Bryson, David Butler, Silvio Caputo, Maria Caserio, Richard Coles, Rachel F. D. Cooper, Raziyeh Farmani, Mark Gaterell, James Hale, Chantal Hales, C. Nicholas Hewitt, Lubo Jankovic, I. Jefferson, J. Leach, A. Rob MacKenzie, Fayyaz Ali Memon, Jon P. Sadler, Carina Weingaertner, J. Duncan Whyatt and Christopher D. F. Rogersadd Show full author list remove Hide full author list
Sustainability 2012, 4(4), 740-772; https://doi.org/10.3390/su4040740 - 20 Apr 2012
Cited by 106 | Viewed by 22011
Abstract
Future scenarios provide challenging, plausible and relevant stories about how the future could unfold. Urban Futures (UF) research has identified a substantial set (>450) of seemingly disparate scenarios published over the period 1997–2011 and within this research, a sub-set of >160 scenarios has [...] Read more.
Future scenarios provide challenging, plausible and relevant stories about how the future could unfold. Urban Futures (UF) research has identified a substantial set (>450) of seemingly disparate scenarios published over the period 1997–2011 and within this research, a sub-set of >160 scenarios has been identified (and categorized) based on their narratives according to the structure first proposed by the Global Scenario Group (GSG) in 1997; three world types (Business as Usual, Barbarization, and Great Transitions) and six scenarios, two for each world type (Policy Reform—PR, Market Forces—MF, Breakdown—B, Fortress World—FW, Eco-Communalism—EC and New Sustainability Paradigm—NSP). It is suggested that four of these scenario archetypes (MF, PR, NSP and FW) are sufficiently distinct to facilitate active stakeholder engagement in futures thinking. Moreover they are accompanied by a well-established, internally consistent set of narratives that provide a deeper understanding of the key fundamental drivers (e.g., STEEP—Social, Technological, Economic, Environmental and Political) that could bring about realistic world changes through a push or a pull effect. This is testament to the original concept of the GSG scenarios and their development and refinement over a 16 year period. Full article
(This article belongs to the Special Issue Advances in Sustainability: Selected Papers from 1st World Sustainability Forum)
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