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Authors = Helmut Wiedenfeld

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6 pages, 277 KiB  
Article
New Compounds from Rhodiola Kirilowii
by Helmut Wiedenfeld, Monika Zych, Waldemar Buchwald and Mirosława Furmanow
Sci. Pharm. 2007, 75(1), 29-34; https://doi.org/10.3797/scipharm.2007.75.29 - 30 Mar 2007
Cited by 23 | Viewed by 2057
Abstract
Five compounds were isolated from root extracts of Rhodiola kirilowii: arbutin, epigallocatechin gallate, rhodiocyanoside A, fructopyrano-(1-4)-glucopyranose and lotaustralin. The first four compounds were found in this plant for the first time. Lotaustralin, salidroside, daucosterol and tyrosol were already described to be contained. [...] Read more.
Five compounds were isolated from root extracts of Rhodiola kirilowii: arbutin, epigallocatechin gallate, rhodiocyanoside A, fructopyrano-(1-4)-glucopyranose and lotaustralin. The first four compounds were found in this plant for the first time. Lotaustralin, salidroside, daucosterol and tyrosol were already described to be contained. Especially salidroside (as a Rhodiola marker compound) could not be detected in our samples. The structures were established by NMR studies. Full article
7 pages, 2249 KiB  
Article
Pvrrolizidine Alkaloid Containina Plants Used in Mongolian Traditional Medicine: Lappula Myosotis Moench.
by Helmut Wiedenfeld, Amarsanaa B., Altanchirneg D. and Narantuya S.
Sci. Pharm. 2005, 73(3), 139-145; https://doi.org/10.3797/scipharm.aut-05-12 - 30 Sep 2005
Cited by 5 | Viewed by 1302
Abstract
Lappula myosotis Moench. (Boraginaceae) is a plant growing wide-spread in the Mongolian Aimags Khubsgul, Khangai, Khentei, Mongol dahurica, Altai and Alasha Gobi [1]. From this plant four pyrrolizidine alkloids were isolated and their structures determined using spectroscopical methods: lycopsamine, intermedine and their acetylderivatives. [...] Read more.
Lappula myosotis Moench. (Boraginaceae) is a plant growing wide-spread in the Mongolian Aimags Khubsgul, Khangai, Khentei, Mongol dahurica, Altai and Alasha Gobi [1]. From this plant four pyrrolizidine alkloids were isolated and their structures determined using spectroscopical methods: lycopsamine, intermedine and their acetylderivatives. This plant is used in the Mongolian traditional medicine externally but on account of its high level of alkaloids (~ 0.2%) the usage of L. myosotis may be hazardous for humans. Full article
4 pages, 1059 KiB  
Article
Pyrrolizidine Alkaloids from Ligularia sibirica Cass. and Tephroseris integrifolia L.
by Helmut Wiedenfeld, S. Narantuya, M. Dumaa and A. Monhbaatar
Sci. Pharm. 2003, 71(2), 129-132; https://doi.org/10.3797/scipharm.aut-03-14 - 28 May 2003
Cited by 5 | Viewed by 1414
Abstract
Tussilagine, isotussilagine, neo-tussilagine and neo-isotussilagine were isolated from Ligularia sibirica whereas Tephroseris integrifolia was found to contain senkirkine, otosenine, hydroxysenkirkine and 07-angeloylheliotridine. The structures were determined using spectroscopical methods (GC-MS; NMR). Full article
5 pages, 1457 KiB  
Article
Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia
by Helmut Wiedenfeld, Narantuya S., Altanchimeg D. and Erhard Roeder
Sci. Pharm. 2000, 68(2), 207-211; https://doi.org/10.3797/scipharm.aut-00-19 - 20 Apr 2000
Cited by 14 | Viewed by 1353
Abstract
We isolated four Pyrrolizidine Alkaloids (PA) from Senecio nemorensis L. growing in Mongolia. Their structures were elucidated by spectroscopic methods to be 7-Senecioyl-9-sarracinoyl-retronecine, Retroisosenine, Doriasenine and Bulgarsenine. The alkaloidal pattern is very similar to that of the European Senecio nemorensis L., ssp. nemorensis [...] Read more.
We isolated four Pyrrolizidine Alkaloids (PA) from Senecio nemorensis L. growing in Mongolia. Their structures were elucidated by spectroscopic methods to be 7-Senecioyl-9-sarracinoyl-retronecine, Retroisosenine, Doriasenine and Bulgarsenine. The alkaloidal pattern is very similar to that of the European Senecio nemorensis L., ssp. nemorensis (Rchb.) Celak. The medicinal use of this plant or of preparations from it may be hazardous to human health because of the high PA level in the plant (≈ 0.1%) and the fact that three of the PA are known to have toxic side-effects. Full article
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