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Authors = Garofita Mateescu ORCID = 0000-0001-8249-6289

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22 pages, 872 KB  
Systematic Review
Update on the Study of Angiogenesis in Surgical Wounds in Patients with Childhood Obesity
by Cristina Chelmu Voda, Ioana Anca Stefanopol, Gabriela Gurau, Maria Andrada Hîncu, Gabriel Valeriu Popa, Olivia Garofita Mateescu, Liliana Baroiu and Mihaela Cezarina Mehedinti
Biomedicines 2025, 13(2), 375; https://doi.org/10.3390/biomedicines13020375 - 5 Feb 2025
Cited by 2 | Viewed by 2408
Abstract
Background: Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a pivotal role in wound healing, particularly in surgical contexts. Methods and results: However, this process can be significantly impaired in patients with childhood obesity, resulting in delayed healing and additional [...] Read more.
Background: Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a pivotal role in wound healing, particularly in surgical contexts. Methods and results: However, this process can be significantly impaired in patients with childhood obesity, resulting in delayed healing and additional complications. The biological process of wound healing is complex, involving angiogenesis, cell proliferation, inflammation, and tissue remodeling. This review aims to explore recent advancements in research on angiogenesis in surgical wounds in patients with childhood obesity, with a focus on growth factors, inflammation, microcirculation, and innovative therapeutic strategies. Conclusions: It highlights therapeutic approaches such as the administration of growth factors and the application of biomaterials to enhance angiogenesis. Full article
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28 pages, 932 KB  
Review
The Clinical Profile of Cat-Scratch Disease’s Neuro-Ophthalmological Effects
by Sanda Jurja, Alina Zorina Stroe, Mihaela Butcaru Pundiche, Silviu Docu Axelerad, Garofita Mateescu, Alexandru Octavian Micu, Raducu Popescu, Antoanela Oltean and Any Docu Axelerad
Brain Sci. 2022, 12(2), 217; https://doi.org/10.3390/brainsci12020217 - 4 Feb 2022
Cited by 15 | Viewed by 11966
Abstract
Cat-scratch disease is an illness caused by Bartonella henselae that occurs as a result of contact with an infected kitten or dog, such as a bite or scratch. It is more prevalent in children and young adults, as well as immunocompromised individuals. There [...] Read more.
Cat-scratch disease is an illness caused by Bartonella henselae that occurs as a result of contact with an infected kitten or dog, such as a bite or scratch. It is more prevalent in children and young adults, as well as immunocompromised individuals. There are limited publications examining the features of CSD in patients. As such, the purpose of this research was to assess the clinical neuro-ophthalmological consequences of CSD reported in the literature. Among the ophthalmologic disorders caused by cat-scratch disease in humans, Parinaud oculoglandular syndrome, uveitis, vitritis, retinitis, retinochoroiditis and optic neuritis are the most prevalent. The neurological disorders caused by cat-scratch disease in humans include encephalopathy, transverse myelitis, radiculitis, and cerebellar ataxia. The current review addresses the neuro-ophthalmological clinical manifestations of cat-scratch disease, as described in papers published over the last four decades (1980–2022). All the data gathered were obtained from PubMed, Medline and Google Scholar. The current descriptive review summarizes the most-often-encountered clinical symptomatology in instances of cat-scratch disease with neurological and ocular invasion. Thus, the purpose of this review is to increase knowledge of cat-scratch disease’s neuro-ophthalmological manifestations. Full article
(This article belongs to the Section Sensory and Motor Neuroscience)
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