- Systematic Review
Early vs. Delayed Repair in Urethral Injuries: A Systematic Review
- Kuncoro Adi and
- Bacilius A. Priyosantoso
Background/Objectives: The optimal timing for definitive repair of urethral injuries, early versus delayed, remains a subject of ongoing debate. While delayed repair has traditionally been favored to allow resolution of local tissue trauma, emerging evidence suggests that early intervention may offer comparable or superior outcomes without increased risk of complications. This systematic review compares outcomes between early and delayed urethral repair across various patient populations and injury types. Methods: A systematic search of PubMed, Embase, and Scopus (through June 2025) was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Comparative studies evaluating early (within initial hospitalization or ≤1 month) versus delayed (>1–3 months post-injury) urethral repair were included. Primary outcomes were urethral stricture formation, erectile dysfunction (ED), and urinary incontinence (UI). Risk of bias was assessed using a modified Newcastle-Ottawa Scale. Results: Of 125 records screened, four retrospective cohort studies met inclusion criteria, encompassing 343 patients with anterior and posterior urethral injuries across pediatric and adult populations. Three studies found no significant difference in stricture, ED, or UI rates between early and delayed repair. One study (Chen et al., 2024) reported higher complication rates in the delayed group (stricture: 47% vs. 22%; ED: 37% vs. 3%; UI: 27% vs. 11%). Across the limited and heterogeneous studies available, no clear superiority was demonstrated between early and delayed urethral repair in terms of long-term stricture and functional outcomes. Conclusions: In carefully selected stable patients, early repair does not increase the risk of complications and may reduce catheterization time. When performed by experienced surgeons, early intervention does not increase stricture, ED, or UI risk, and may improve overall morbidity. Patient selection remains critical, but routine deferral of urethroplasty for several months should be reconsidered.
15 December 2025



