Risk Factors for Male Reproductive Health

Dear Colleagues,

Evidence of low sperm concentrations and an increasing number of abnormalities of the male reproductive system, such as cryptorchidism and germ cell tumors, have prompted researchers to declare male reproductive health to be in a state of global emergency.

Male factors, reflected primarily in semen quality, account for half of the identifiable causes of couple infertility, and multiple studies demonstrate an association between male infertility and overall health.

Health-behavioral, psychosocial, environmental, genetic, endocrine, metabolic, immunologic, and epigenetic factors may all play important roles. However, their interplay and relative contributions are poorly understood, as is our insight into the underlying mechanisms and pathogenic processes in different stages of life.

In this Special Issue, we invite epidemiological research on risk factors for male reproductive health. This includes original articles, reviews, and communications on topics such as:

• Associations between risk factors and male reproductive health, including but not limited to semen parameters, reproductive hormones, urogenital, and cancer of the testes;
• Exposures before and during the early development period (i.e., preconceptional, in utero, infancy, and childhood puberty, mini-puberty) that might be more vulnerable to exposures;
• Male-mediated toxicity and heritable conditions that the father can pass on to offspring;
• Biological pathways or mechanisms;
• Interactions and mixture effects related to endocrine disrupting chemicals’ health behaviors, and other exposure types;
• Less studied and novel risk factors in addition to ‘classical’ exposures.

With your insights, this Special Issue has the potential to significantly impact the current state of male reproductive health. We look forward to receiving your contributions.

Dr. Sandra Søgaard Tøttenborg
Prof. Jens Peter Bonde
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Reproductive Medicine is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Male infertility
• Male reproduction
• Testis cancer
• Endocrine disrupting chemicals
• Reproductive epidemiology
• Male-mediated toxicity
• Semen quality
• Environment
• Spermatozoa
• Hormones