21 April 2023
Journal of Clinical Medicine Webinar | The Future of COVID-19 mRNA Vaccines: Focus on Innate Immunity, 10 May 2023

COVID-19 mRNA vaccines saved millions of lives during the pandemic crisis by efficiently protecting against the severe forms of the disease. However, they were much less efficient in protecting against the infection itself and viral transmission. Furthermore, the immunity induced by these vaccines proved to wane relatively rapidly. To understand these features and possibly improve the efficacy and safety of mRNA vaccines, it is critical to obtain insight into their action on the innate immune system.

During this webinar, we will first review the current knowledge on adjuvants included in protein-based vaccines and their action on the innate immune system. We will then discuss how lipid nanoparticles and nucleoside-modified mRNA—the two major components of currently approved mRNA vaccines—contribute to the activation of the innate immune system required for the induction of protective immunity. Finally, we will consider the consequences of this activation on the immune defenses against other pathogens through the phenomenon of trained immunity.

Date: 10 May 2023 at 10:00 a.m. CEST | 4:00 a.m. EST | 3:00 a.m. CST Asia

Webinar ID: 871 5675 7294

Register now for free!

Speaker/Presentation

Time in CEST

Time in EST

Prof. Dr. Michel Goldman
Chair Introduction

10:00—10:05 a.m.

4:00—4:05 a.m.

Dr. Nathalie Garçon
Lessons Learned from Vaccine Adjuvants

10:05—10:35 a.m.

4:05—4:35 a.m.

Dr. Rein Verbeke
The Adjuvant Properties of mRNA-LNP Vaccines

10:35—11:05 a.m.

4:35—5:05 a.m.

Dr. Mihai Netea
How to Leverage Trained Immunity?

11:05—11:35 a.m.

5:05—5:35 a.m.

Q&A Session

11:35—11:55 a.m.

5:35—5:55 a.m.

Prof. Michel Goldman
Closing of Webinar

11:55—12:00 p.m.

5:55—6:00 a.m.

Webinar Chairs and Keynote Speakers:

Prof. Dr. Michel Goldman (Chair), Institute for Interdisciplinary Innovation in healthcare, Université libre de Bruxelles, Brussels, Belgium
Dr. Nathalie Garçon (Co-Chair), N3J Consulting, Belgium
Dr. Rein Verbeke, 1 Ghent Research Group on Nanomedicines, Ghent University, Ghent, Belgium; 2 Cancer Research Institute Ghent (CRIG), Ghent, Belgium
Dr. Mihai Netea, 1 Department of Internal Medicine, Radboud Institute of Molecular Life Sciences (RIMLS) and Radboudumc Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands; 2Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany

Relevant Special Issue:
Learning from COVID-19 Vaccines
Guest Editor: Prof. Dr. Michel Goldman

After registering, you will receive a confirmation email containing information on how to join the webinar. Registrations with academic institutional email addresses will be prioritized.

Unable to attend? Register anyway and we will let you know when the recording is available to watch.

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