The “Gene and Cell Therapy” Section publishes reviews and original peer-reviewed papers. This section of Biomedicines aims to rapidly publish contributions on all aspects of the latest research results concerning gene and cell therapy. We encourage submissions of manuscripts that provide novel and mechanistic insights, including but not limited to gene transfer; vector development and design; autologous and allogeneic cell therapies (hematopoietic and mesenchymal stem cell therapies); the development of genes, peptides, proteins, oligonucleotides, and cell therapies to correct genetic and acquired diseases; vaccine development; preclinical target validation; and other research aspects. In this context, we are pleased to feature some recently published papers from the “Gene and Cell Therapy” Section in Biomedicines (ISSN: 2227-9059), which will provide valuable insights into this exciting field.

1. “Protective Effects of High-Density Lipoprotein on Cancer Risk: Focus on Multiple Myeloma”
by Alessandro Allegra, Giuseppe Murdaca, Giuseppe Mirabile and Sebastiano Gangemi
Biomedicines 2024, 12(3), 514; https://doi.org/10.3390/biomedicines12030514
Available online: https://www.mdpi.com/2227-9059/12/3/514

2. “MicroRNA Monitoring in Human Alveolar Macrophages from Patients with Smoking-Related Lung Diseases: A Preliminary Study”
by Davida Mirra, Renata Esposito, Giuseppe Spaziano, Liberata Sportiello, Francesca Panico, Antonio Squillante, Maddalena Falciani, Ida Cerqua , Luca Gallelli, Erika Cione and Bruno D’Agostino
Biomedicines 2024, 12(5), 1050; https://doi.org/10.3390/biomedicines12051050
Available online: https://www.mdpi.com/2227-9059/12/5/1050

3. “Biomarkers and Signaling Pathways Implicated in the Pathogenesis of Idiopathic Multicentric Castleman Disease/Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Renal Insufficiency, and Organomegaly (TAFRO) Syndrome”
by Remi Sumiyoshi, Tomohiro Koga and Atsushi Kawakami
Biomedicines 2024, 12(6), 1141; https://doi.org/10.3390/biomedicines12061141
Available online: https://www.mdpi.com/2227-9059/12/6/1141

4. “Structural Changes Likely Cause Chemical Differences between Empty and Full AAV Capsids”
by Caryn L. Heldt, Molly A. Skinner and Ganesh S. Anand
Biomedicines 2024, 12(9), 2128; https://doi.org/10.3390/biomedicines12092128
Available online: https://www.mdpi.com/2227-9059/12/9/2128

5. “Long-Term Follow-Up of Phase I Trial of Oncolytic Adenovirus-Mediated Cytotoxic and Interleukin-12 Gene Therapy for Treatment of Metastatic Pancreatic Cancer”
by Aseem Rai Bhatnagar, Farzan Siddiqui, Gazala Khan, Robert Pompa, David Kwon and Shyam Nyati
Biomedicines 2024, 12(5), 1065; https://doi.org/10.3390/biomedicines12051065
Available online: https://www.mdpi.com/2227-9059/12/5/1065

6. “Potential Causal Association between C-Reactive Protein Levels in Age-Related Macular Degeneration: A Two-Sample Mendelian Randomization Study”
by Byung Woo Yoon, Young Lee and Je Hyun Seo
Biomedicines 2024, 12(4), 807; https://doi.org/10.3390/biomedicines12040807
Available online: https://www.mdpi.com/2227-9059/12/4/807

7. “A Comprehensive Exploration of Therapeutic Strategies in Inflammatory Bowel Diseases: Insights from Human and Animal Studies”
by Inês Esteves Dias, Isabel Ribeiro Dias, Teresa Franchi-Mendes, Carlos Antunes Viegas and Pedro Pires Carvalho
Biomedicines 2024, 12(4), 735; https://doi.org/10.3390/biomedicines12040735
Available online: https://www.mdpi.com/2227-9059/12/4/735

8. “Regenerative Therapy for Corneal Scarring Disorders”
by Christine Chandran, Mithun Santra, Elizabeth Rubin, Moira L. Geary and Gary Hin-Fai Yam
Biomedicines 2024, 12(3), 649; https://doi.org/10.3390/biomedicines12030649
Available online: https://www.mdpi.com/2227-9059/12/3/649

9. “Application of SWATH Mass Spectrometry and Machine Learning in the Diagnosis of Inflammatory Bowel Disease Based on the Stool Proteome”
by Elmira Shajari, David Gagné, Mandy Malick, Patricia Roy, Jean-François Noël, Hugo Gagnon, Marie A. Brunet, Maxime Delisle, François-Michel Boisvert and Jean-François Beaulieu
Biomedicines 2024, 12(2), 333; https://doi.org/10.3390/biomedicines12020333
Available online: https://www.mdpi.com/2227-9059/12/2/333

10. “CAR NK92 Cells Targeting BCMA Can Effectively Kill Multiple Myeloma Cells Both In Vitro and In Vivo”
by Eunhee Park, Hui-jin Mun, Eunju Seo, Seojin Hwang, Jae Hee Lee, Sukgil Song, Hyeran Sung, Hoi-Yul Kim and Mi-Jin Kwon
Biomedicines 2024, 12(1), 248; https://doi.org/10.3390/biomedicines12010248
Available online: https://www.mdpi.com/2227-9059/12/1/248

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:

This Section is currently open for submissions. Papers may be submitted via the following link:

https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:

If you are an active researcher in the field of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office