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Volume 2
Issue 4
10.3390/pets2040034
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Case Report

Diagnosis, Management, and Long-Term Outcome of Esophageal Plasmacytoma in a Dog

by
Katerina T. Moraiti
1,*,
Ioanna Papavasileiou
2,
Evgenia Flouraki
3,
Vasiliki Tsioli
3,
Shelley J. Newman
4,
Joao P. Cavasin
5 and
Panagiotis G. Xenoulis
1
1
Clinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece
2
Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece
3
Clinic of Surgery, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece
4
Newman Specialty VetPath, Hicksville, NY 11801, USA
5
Gastrointestinal Laboratory, Small Animal Clinical Sciences, Texas A&M University, College Station, TX 77845, USA
*
Author to whom correspondence should be addressed.
Pets 2025, 2(4), 34; https://doi.org/10.3390/pets2040034 (registering DOI)
Submission received: 26 July 2025 / Revised: 25 September 2025 / Accepted: 30 September 2025 / Published: 5 October 2025
Review Reports Versions Notes

Abstract

A nine-year-old, 10.5 kg, female-spayed Poodle-mix dog presented with a five-day history of vomiting and regurgitation. Thoracic radiographs revealed an area with increased opacity within the esophageal lumen. A ductal esophageal lesion with intraluminal extension and mild left axillary lymphadenopathy were detected on computed tomography. Esophagoscopy revealed a large vascular, obstructive mass with a smooth surface, in the mid part of the esophagus. Endoscopic biopsies were collected, and histopathologic findings were consistent with an inflammatory polyp. Surgical excision of the mass via sternotomy was performed and the mass was sent for histopathologic evaluation. Histopathological examination of the mass revealed an esophageal plasmacytoma with perivascular amyloid deposition, which was confirmed by immunohistochemical staining. There was no evidence of regrowth until 18 months after surgical removal, when evidence of regrowth was identified. The dog had only one episode of vomiting and regurgitation which was resolved after symptomatic treatment.
Keywords: canine; esophageal tumor; plasma cell tumor; esophagus canine; esophageal tumor; plasma cell tumor; esophagus

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MDPI and ACS Style

Moraiti, K.T.; Papavasileiou, I.; Flouraki, E.; Tsioli, V.; Newman, S.J.; Cavasin, J.P.; Xenoulis, P.G. Diagnosis, Management, and Long-Term Outcome of Esophageal Plasmacytoma in a Dog. Pets 2025, 2, 34. https://doi.org/10.3390/pets2040034

AMA Style

Moraiti KT, Papavasileiou I, Flouraki E, Tsioli V, Newman SJ, Cavasin JP, Xenoulis PG. Diagnosis, Management, and Long-Term Outcome of Esophageal Plasmacytoma in a Dog. Pets. 2025; 2(4):34. https://doi.org/10.3390/pets2040034

Chicago/Turabian Style

Moraiti, Katerina T., Ioanna Papavasileiou, Evgenia Flouraki, Vasiliki Tsioli, Shelley J. Newman, Joao P. Cavasin, and Panagiotis G. Xenoulis. 2025. "Diagnosis, Management, and Long-Term Outcome of Esophageal Plasmacytoma in a Dog" Pets 2, no. 4: 34. https://doi.org/10.3390/pets2040034

APA Style

Moraiti, K. T., Papavasileiou, I., Flouraki, E., Tsioli, V., Newman, S. J., Cavasin, J. P., & Xenoulis, P. G. (2025). Diagnosis, Management, and Long-Term Outcome of Esophageal Plasmacytoma in a Dog. Pets, 2(4), 34. https://doi.org/10.3390/pets2040034

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