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Journal of Clinical & Translational Ophthalmology, Volume 2, Issue 3

2024 September - 4 articles

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Articles (4)

  • Systematic Review
  • Open Access
3,504 Views
14 Pages

Rapamycin’s Impact on Age-Related Macular Degeneration—A Systematic Review and Hormesis Perspective

  • Knut Sandok Wigestrand,
  • Santosh Gupta,
  • Kulbhushan Sharma and
  • Goran Petrovski

Background: Pre-clinical studies related to the use of rapamycin (Sirolimus®), a mammalian target of rapamycin (mTOR) inhibitors, for age-related macular degeneration (AMD) have shown improved therapeutic outcomes. However, knowledge of its dose&...

  • Article
  • Open Access
2,213 Views
12 Pages

Possible Correlation between Mucin Gene Expression and Symptoms of Dry Eye Syndrome Secondary to Sjogren’s Disease

  • Natalie Brossard-Barbosa,
  • Matias Agoglia,
  • Maria Elena Vergara,
  • Monique Costa,
  • Ernesto Cairoli and
  • Teresa Freire

(1) Background: It is estimated that 10% of dry eye disease (DED) occurs in patients with Sjogren’s syndrome (SS-DED) and represents a challenge when it comes to treatment. Both innate and adaptive immunity participate in the pathogenesis of SS...

  • Opinion
  • Open Access
2,539 Views
8 Pages

With increasing space exploration, there is a rising need to evaluate the impact of spaceflight on astronauts’ health, including the effects of space-associated hazards such as microgravity. Astronauts’ reports of experienced symptoms upo...

  • Review
  • Open Access
1 Citations
7,390 Views
15 Pages

Hereditary Optic Neuropathies: An Updated Review

  • Samuel K. Lee,
  • Caroline Mura,
  • Nicolas J. Abreu,
  • Janet C. Rucker,
  • Steven L. Galetta,
  • Laura J. Balcer and
  • Scott N. Grossman

Hereditary optic neuropathies (HONs) are a class of genetic disorders that may lead to vision loss due to either acute or progressive injury to the optic nerve. Although HONs may commonly manifest as isolated optic atrophy, these disorders can also h...

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J. Clin. Transl. Ophthalmol. - ISSN 2813-1053