HHV-6 in Cerebrospinal Fluid in Immunocompetent Children
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Age, Months | Gender | Symptoms | CSF | Plasma | WBC | Diagnosis | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
HHV-6 | Cell Count (Cell/3 Mics) | Protein (g/L) | Glucose (mmol/L) | Another Agent in CSF | HHV-6 | Another Agent | |||||
23 | m | Fever, lethargy, rash | Positive | 3 | 0.08 | 4.2 | Negative | Not tested | Negative | Leucopenia | ES ** |
14 | m | Fever, repeated seizures, rash | Positive | 1 | 0.05 | 3.8 | Negative | Not tested | Negative | Normal | ES + FS *** |
26 | f | Fever, repeated seizures, headache, vomiting, nuchal rigidity, Kernig’s sign, rash | Positive | 3 | 0.2 | 3.3 | Negative | Positive | Negative | Leucopenia | ES + FS |
7 | m | Fever, refusal to eat, irritability, mild transaminitis (ALT = 370) | Positive | 6 | 0.2 | 3.0 | Negative | Positive | Negative | Leucopenia | Fever without rash |
15 | f | Repeated fever, drowsiness, rash | Positive | 18 (PMN * 5) | 0.19 | 3.5 | Negative | Not tested | Meningococcus B | Leucopenia | Meningococcal B inf. + ES |
17 | f | Prolonged fever, drowsiness, rash | Positive | 3 | 0.12 | 3.8 | Negative | Negative | Negative | Leukocytosis, lymphocytosis | Kawasaki disease + ES |
5 | m | Fever, prolonged repeated seizures, lethargy, unconsciousness | Positive | 176 (PMN 90) | 0.22 | 4.9 | Negative | Negative | Bordetella pertussis | Leukocytosis, lymphocytosis | HHV-6-meningoencephalitis + Pertussis |
8 | f | Fever, repeated seizures, lethargy | Positive | 16 (PMN 10) | 1.2 | 2.9 | Negative | Positive | Negative | Normal | HHV-6-meningoencephalitis |
22 | f | Fever, lethargy, vomiting, hallucinations, grimaces, hand twitching, rash | Positive | 590 (PMN 550) | 0.26 | 2.6 | VZV | Negative | VZV | Normal | HHV-6 + VZV-meningoencephalitis |
1 | m | Fever, prolonged repeated seizures, lethargy, general cerebral symptoms, rash | Positive | 3 | 0.44 | 1 | Negative | Positive | VZV | Normal | HHV-6 + VZV-encephalitis |
19 | m | Fever, vomiting, nuchal rigidity, Kernig’s sign | Positive | 2780 (PMN 95%) | 0.35 | 2.1 | Negative | Not tested | Negative | Normal | Bacterial meningitis unknown etiology |
12 | f | Fever, vomiting, nuchal rigidity, Kernig’s sign | Positive | 23,296 (PMN 98%) | 1.4 | 0.5 | Hib | Not tested | Negative | Leukocytosis, neutrophilia | Hib-meningitis |
92 | m | Fever, photophobia, Kernig’s sign | Positive | 870 (PMN 263) | 0.3 | 5.3 | Enterovirus | Not tested | Enterovirus | Normal | Enterovirus meningitis |
62 | f | Fever, headache, vomiting, nuchal rigidity | Positive | 542 (PMN 15) | 0.44 | 2.5 | Enterovirus | Negative | Negative | Normal | Enterovirus meningitis |
11 | f | Fever, nuchal rigidity, lethargy, rash | Positive | 80 (PMN 61) | 1.6 | 4.1 | Pneumococcus | Not tested | Negative | Leukocytosis, neutrophilia | Recurrent acute otitis media |
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Nikolskiy, M.A.; Lioznov, D.A.; Gorelik, E.U.; Vishnevskaya, T.V. HHV-6 in Cerebrospinal Fluid in Immunocompetent Children. BioMed 2023, 3, 420-430. https://doi.org/10.3390/biomed3030034
Nikolskiy MA, Lioznov DA, Gorelik EU, Vishnevskaya TV. HHV-6 in Cerebrospinal Fluid in Immunocompetent Children. BioMed. 2023; 3(3):420-430. https://doi.org/10.3390/biomed3030034
Chicago/Turabian StyleNikolskiy, Mikhail A., Dmitriy A. Lioznov, Evgeniy U. Gorelik, and Tatyana V. Vishnevskaya. 2023. "HHV-6 in Cerebrospinal Fluid in Immunocompetent Children" BioMed 3, no. 3: 420-430. https://doi.org/10.3390/biomed3030034