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Review

Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified

1
Private Practice, Falls Church, VA 22042, USA
2
Private Practice, Mumbai 400059, India
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Author to whom correspondence should be addressed.
Academic Editor: Eugenio Pedullà
Oral 2021, 1(3), 236-249; https://doi.org/10.3390/oral1030023
Received: 15 May 2021 / Revised: 8 July 2021 / Accepted: 28 July 2021 / Published: 11 August 2021
The aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus, ScienceDirect, and Google Search databases. The article reviews contemporary and classic literature with a focus on pathophysiology, clinical presentation, and risk factors associated with this condition. The application of various treatment options is also discussed. Study selection: Clinical studies, systematic reviews, in vitro studies, and case reports. Conclusion: Dental plaque, genetic predisposition, and type of drug used are critical in the development of drug-influenced gingival enlargement (DIGE). The surgical technique employed to treat the pathosis plays an important role in long term success of therapy. There has been an upward trend in occurrence of CCB-influenced gingival enlargement due to the unbridled use of CCBs. Due to the cosmetic and functional ramifications; the review underscores the importance of clinical research on prevention, treatment, and causes of recurrence of CCB-influenced gingival enlargement. View Full-Text
Keywords: drug-influenced gingival enlargement; calcium channel blockers; adverse drug reactions; side effect; nifedipine; amlodipine drug-influenced gingival enlargement; calcium channel blockers; adverse drug reactions; side effect; nifedipine; amlodipine
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MDPI and ACS Style

Tonsekar, P.; Tonsekar, V. Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified. Oral 2021, 1, 236-249. https://doi.org/10.3390/oral1030023

AMA Style

Tonsekar P, Tonsekar V. Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified. Oral. 2021; 1(3):236-249. https://doi.org/10.3390/oral1030023

Chicago/Turabian Style

Tonsekar, Pallavi, and Vidya Tonsekar. 2021. "Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified" Oral 1, no. 3: 236-249. https://doi.org/10.3390/oral1030023

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