The Global Burden of Sepsis and Septic Shock
Abstract
:1. Introduction
2. Methods
3. How Did the Definition of Sepsis Change over Time?
4. What Is the Epidemiology of Sepsis and Septic Shock?
5. What Are the Risk Factors and Comorbidities across Continents?
6. What Are the Differences in Diagnosis and Clinical Management across Various Healthcare Settings?
7. What Is the Magnitude of the Economic Burden and Healthcare Costs across Continents?
8. What Prevention Strategies and Quality Improvement Initiatives May Be Promoted Worldwide?
9. What Are Challenges and Future Directions in Global Sepsis Management?
10. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Study | Country/Region | Period | Population | Key Findings |
---|---|---|---|---|
Fleischmann et al. (2016) [4] | Global | 1990–2017 | Hospital-treated patients |
|
Rudd et al. (2020) [5] | Global | 2017 | General population |
|
Angus et al. (2001) [43] | United States | 1995 | Hospital-treated patients |
|
Ahmed et al. (2021) [25] | Pakistan | 2013–2014 | Adult patients with sepsis or septic shock |
|
Weng et al. (2023) [24] | China | 2017–2019 | Hospitalized patients with sepsis |
|
Study | Country/Region | Population | Study Design | Key Findings | Implications |
---|---|---|---|---|---|
Rhodes et al. (2017) [34] | International | Adult patients with sepsis and septic shock | Evidence-based guideline |
|
|
Schultz et al. (2017) [8] | Low- and middle-income countries (LMICs) | Patients with sepsis and septic shock | Review article |
|
|
Levy et al. (2018) [90] | International | Adult patients with sepsis and septic shock | Guideline update |
|
|
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La Via, L.; Sangiorgio, G.; Stefani, S.; Marino, A.; Nunnari, G.; Cocuzza, S.; La Mantia, I.; Cacopardo, B.; Stracquadanio, S.; Spampinato, S.; et al. The Global Burden of Sepsis and Septic Shock. Epidemiologia 2024, 5, 456-478. https://doi.org/10.3390/epidemiologia5030032
La Via L, Sangiorgio G, Stefani S, Marino A, Nunnari G, Cocuzza S, La Mantia I, Cacopardo B, Stracquadanio S, Spampinato S, et al. The Global Burden of Sepsis and Septic Shock. Epidemiologia. 2024; 5(3):456-478. https://doi.org/10.3390/epidemiologia5030032
Chicago/Turabian StyleLa Via, Luigi, Giuseppe Sangiorgio, Stefania Stefani, Andrea Marino, Giuseppe Nunnari, Salvatore Cocuzza, Ignazio La Mantia, Bruno Cacopardo, Stefano Stracquadanio, Serena Spampinato, and et al. 2024. "The Global Burden of Sepsis and Septic Shock" Epidemiologia 5, no. 3: 456-478. https://doi.org/10.3390/epidemiologia5030032
APA StyleLa Via, L., Sangiorgio, G., Stefani, S., Marino, A., Nunnari, G., Cocuzza, S., La Mantia, I., Cacopardo, B., Stracquadanio, S., Spampinato, S., Lavalle, S., & Maniaci, A. (2024). The Global Burden of Sepsis and Septic Shock. Epidemiologia, 5(3), 456-478. https://doi.org/10.3390/epidemiologia5030032