Pilot Scale Extraction of Orthosiphon stamineus Raw Material as Rosmarinic Acid Extract
Abstract
:1. Introduction
2. Materials and Methods
2.1. Plant Material
2.2. Preparative Scale and Pilot Scale Reflux Extraction
2.3. Quantification of Rosmarinic Acid by HPLC-DAD
2.4.Scaling up Rosmarinic Acid Extraction
- i.
- The extraction was an isothermal and isobaric process;
- ii.
- The preparative- and pilot-scale extraction vessels were geometrically similar;
- iii.
- The stirred vessel system was fully turbulent.
3. Results and Discussion
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Properties | Preparative-Scale Extractor | Pilot-Scale Extractor |
---|---|---|
Vessel volume, Vvessel (m3) | 0.005 | 0.013 |
Working volume, Vworking(m3) | 0.0025 | 0.01 |
Vessel diameter, T (m) | 0.18 | 0.2 |
Liquid level, z (m) | 0.0918 | 0.3183 |
Impeller diameter, D (m) | 0.06 | 0.07 |
Liquid density, ρL (kg/m3) | 878.8 | |
Liquid viscosity, μ (Pa·s) | 0.002225 | |
Scale-up with constant power dissipation (P/V) | ||
Agitation speed, N (rpm) | 500 | 451 |
Reynolds number, Re | 11,849.5 | 14,547.9 |
(Fully turbulent) | (Fully turbulent) | |
Top speed, πND | 1.57 | 1.65 |
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Lau, C.H.; Chua, L.S. Pilot Scale Extraction of Orthosiphon stamineus Raw Material as Rosmarinic Acid Extract. AgriEngineering 2019, 1, 94-99. https://doi.org/10.3390/agriengineering1010007
Lau CH, Chua LS. Pilot Scale Extraction of Orthosiphon stamineus Raw Material as Rosmarinic Acid Extract. AgriEngineering. 2019; 1(1):94-99. https://doi.org/10.3390/agriengineering1010007
Chicago/Turabian StyleLau, Cher Haan, and Lee Suan Chua. 2019. "Pilot Scale Extraction of Orthosiphon stamineus Raw Material as Rosmarinic Acid Extract" AgriEngineering 1, no. 1: 94-99. https://doi.org/10.3390/agriengineering1010007