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When Clinical History Addresses the Diagnosis in a Case of Uncommon Meningitis

Intensive Care Unit of Annunziata Hospital, 87100 Cosenza, Italy
Department of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018-2022, University of Calabria, 87036 Rende (C.S.), Italy
Unit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging (INRCA), 87100 Cosenza, Italy
Department of Microbiology and Virology, Pugliese Ciaccio Hospital, 88100 Catanzaro, Italy
Department of Health Science, University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Azienda Ospedaliera MaterDomini, 88100 Catanzaro, Italy
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Reports 2019, 2(1), 10;
Received: 4 February 2019 / Revised: 6 March 2019 / Accepted: 8 March 2019 / Published: 11 March 2019
PDF [157 KB, uploaded 11 March 2019]


Migraine pain is usually cyclic and may be evocated by inflammatory mediators released around the nerves and blood vessels. Acute migraine pain is more common in women than in men, and correlates with age. In this study, we report the development of an acute migraine attack in a young man (32 years old), which led to his admission to the emergency department. The positive functional brain changes recorded by electroencephalogram (EEG) during the migraine attack, and the non-contrast brain computed tomography scan showed the presence of an arachnoid cyst, which explained the acute migraine attack inducing a misdiagnosis. Using the case described herein, we aim to draw the attention of clinic/scientific communities toward the existence of brain infections in absence of the typical symptoms (e.g., fever and/or rigor nucalis). Considering this case, we propose that when a diagnosis is uncertain the invasive liquor test should be performed. View Full-Text
Keywords: migraine; infection; clinical history migraine; infection; clinical history
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Luciani, F.; Cione, E.; Caroleo, M.C.; Corsonello, A.; Colosimo, M.; Gallelli, L. When Clinical History Addresses the Diagnosis in a Case of Uncommon Meningitis. Reports 2019, 2, 10.

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