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Case Report

Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma

by
Yuika Sasatani
,
Shinichiro Okauchi
,
Gen Ohara
,
Katsunori Kagohashi
,
Kesato Iguchi
,
Koji Kawai
and
Hiroaki Satoh
*
Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Miya-machi 3-2-7, Mito 310-0015, Ibaraki, Japan
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2019, 87(5), 301-304; https://doi.org/10.5603/ARM.2019.0053
Submission received: 17 June 2019 / Revised: 2 September 2019 / Accepted: 2 September 2019 / Published: 31 October 2019

Abstract

Anaplastic lymphoma kinase rearranged non-small-cell lung cancer is arare disease. Among them, asubset of patients exist who exhibit relatively slowly progressing symptoms and have oligo-metastases. In this article, we present two cases of ALK rearran-ged lung adenocarcinoma in patients who experienced postoperative oligo-recurrence. Both cases were treated with surgical resection and gamma knife irradiation for oligo-recurrence. After local therapy, the first patient remained disease free for over 23 months; the second for over 18 months. It appears that some patients with ALK rearranged NSCLC experience oligo-recurrence in their clinical course. For such patients, appropriate local therapy may be beneficial in improving both the quality of life and the prognosis.
Keywords: oligo-recurrence; local therapy; ALK rearrangement oligo-recurrence; local therapy; ALK rearrangement

Share and Cite

MDPI and ACS Style

Sasatani, Y.; Okauchi, S.; Ohara, G.; Kagohashi, K.; Iguchi, K.; Kawai, K.; Satoh, H. Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma. Adv. Respir. Med. 2019, 87, 301-304. https://doi.org/10.5603/ARM.2019.0053

AMA Style

Sasatani Y, Okauchi S, Ohara G, Kagohashi K, Iguchi K, Kawai K, Satoh H. Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma. Advances in Respiratory Medicine. 2019; 87(5):301-304. https://doi.org/10.5603/ARM.2019.0053

Chicago/Turabian Style

Sasatani, Yuika, Shinichiro Okauchi, Gen Ohara, Katsunori Kagohashi, Kesato Iguchi, Koji Kawai, and Hiroaki Satoh. 2019. "Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma" Advances in Respiratory Medicine 87, no. 5: 301-304. https://doi.org/10.5603/ARM.2019.0053

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