Next Article in Journal
A Late Presentation of an Uncommon Congenital Vascular Anomaly
Previous Article in Journal
Neurogenic Pulmonary Oedema as a Rare Complication of Epileptic Seizures
Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on as a courtesy and upon agreement with Via Medica.
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Case Report

Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma

Yuika Sasatani
Shinichiro Okauchi
Gen Ohara
Katsunori Kagohashi
Kesato Iguchi
Koji Kawai
Hiroaki Satoh
Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Miya-machi 3-2-7, Mito 310-0015, Ibaraki, Japan
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2019, 87(5), 301-304;
Submission received: 17 June 2019 / Revised: 2 September 2019 / Accepted: 2 September 2019 / Published: 31 October 2019


Anaplastic lymphoma kinase rearranged non-small-cell lung cancer is arare disease. Among them, asubset of patients exist who exhibit relatively slowly progressing symptoms and have oligo-metastases. In this article, we present two cases of ALK rearran-ged lung adenocarcinoma in patients who experienced postoperative oligo-recurrence. Both cases were treated with surgical resection and gamma knife irradiation for oligo-recurrence. After local therapy, the first patient remained disease free for over 23 months; the second for over 18 months. It appears that some patients with ALK rearranged NSCLC experience oligo-recurrence in their clinical course. For such patients, appropriate local therapy may be beneficial in improving both the quality of life and the prognosis.
Keywords: oligo-recurrence; local therapy; ALK rearrangement oligo-recurrence; local therapy; ALK rearrangement

Share and Cite

MDPI and ACS Style

Sasatani, Y.; Okauchi, S.; Ohara, G.; Kagohashi, K.; Iguchi, K.; Kawai, K.; Satoh, H. Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma. Adv. Respir. Med. 2019, 87, 301-304.

AMA Style

Sasatani Y, Okauchi S, Ohara G, Kagohashi K, Iguchi K, Kawai K, Satoh H. Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma. Advances in Respiratory Medicine. 2019; 87(5):301-304.

Chicago/Turabian Style

Sasatani, Yuika, Shinichiro Okauchi, Gen Ohara, Katsunori Kagohashi, Kesato Iguchi, Koji Kawai, and Hiroaki Satoh. 2019. "Oligo-Recurrence from Anaplastic Lymphoma Kinase-Rearranged Lung Adenocarcinoma" Advances in Respiratory Medicine 87, no. 5: 301-304.

Article Metrics

Back to TopTop