Next Article in Journal
The Effectiveness of Bronchial Artery Embolisation in Patients with Haemoptysis
Previous Article in Journal
HIV Status among Presumptive Tuberculosis Cases Attending Tertiary Care Centre in South India
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
ARM
Volume 86
Issue 5
10.5603/ARM.2018.0034
arm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens

by
Armin Krvavac
1,
Kurt Munzer
2,
Aaron Miller
2,
Nishant Poddar
3,
Zafar Jamkhana
2 and
Setu Patolia
2,*
1
Division of Pulmonary and Critical Care, University of Missouri, Columbia, MO 65211, USA
2
Division of Pulmonary and Critical Care, Saint Louis University, St. Louis, MO, USA
3
Division of Oncology, Saint Louis University, St. Louis, MO, USA
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2018, 86(5), 215-219; https://doi.org/10.5603/ARM.2018.0034
Submission received: 23 July 2018 / Revised: 21 September 2018 / Accepted: 21 September 2018 / Published: 30 October 2018

Abstract

Introduction: Granulomatous inflammation has been associated with malignancies such as breast, testicular, renal cell, and lymphoma. The coexistence of granulomatous inflammation in mediastinal/hilar lymph node with primary lung malignancy has been described in Case Reports. Our goal was to examine the frequency of granulomatous reaction in mediastinal/hilar lymph node in the patients who had undergone surgical resection of lung cancer. Material and methods: We performed a retrospective analysis of 40 patients (1) aged ≥ 18 years and (2) who underwent lobectomy or pneumonectomy from 1 August 2012 to 31 October 2016 at Saint Louis University Hospital and (3) had pathology suggestive of cancer. Results: Of those 40 patients, 3 (7.5%) had granulomatous inflammation in the lymph nodes. None of these 3 individuals had evidence of metastasis in the particular lymph nodes with granulomatous inflammation. Conclusion: Our small cohort revealed that the presence of granulomatous inflammation in a lymph node can be safely taken as an evidence of the absence of metastasis to the lymph node. This finding can obviate the need for further sampling for the particular lymph node with granulomatous inflammation and can decrease the sampling time.
Keywords: biopsy; bronchoscopy; lung neoplasm; lymph nodes; sarcoidosis biopsy; bronchoscopy; lung neoplasm; lymph nodes; sarcoidosis

Share and Cite

MDPI and ACS Style

Krvavac, A.; Munzer, K.; Miller, A.; Poddar, N.; Jamkhana, Z.; Patolia, S. The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens. Adv. Respir. Med. 2018, 86, 215-219. https://doi.org/10.5603/ARM.2018.0034

AMA Style

Krvavac A, Munzer K, Miller A, Poddar N, Jamkhana Z, Patolia S. The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens. Advances in Respiratory Medicine. 2018; 86(5):215-219. https://doi.org/10.5603/ARM.2018.0034

Chicago/Turabian Style

Krvavac, Armin, Kurt Munzer, Aaron Miller, Nishant Poddar, Zafar Jamkhana, and Setu Patolia. 2018. "The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens" Advances in Respiratory Medicine 86, no. 5: 215-219. https://doi.org/10.5603/ARM.2018.0034

APA Style

Krvavac, A., Munzer, K., Miller, A., Poddar, N., Jamkhana, Z., & Patolia, S. (2018). The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens. Advances in Respiratory Medicine, 86(5), 215-219. https://doi.org/10.5603/ARM.2018.0034

Article Metrics

Back to TopTop