On Concept of Hybrid in Colloid Sciences

Round 1

Reviewer 1 Report

In this work, an historical background on the formation of hybrids some case are reported based on modern colloid formulations.

This manuscript is original, interesting, well-structured, and valuable to readers and it can be considered for publication in the journal of Colloids and Interfaces after some small modifications:

• Line 363: Liposome is one type of vesicle.
• Line 408. Instead of strategy could it be better to say preparation method?
• The use of a table in which the main applications of hybrid colloids, regarding type of NP and polymers used,  preparation method, size and shape.

Author Response

In this work, an historical background on the formation of hybrids some case are reported based on modern colloid formulations.

This manuscript is original, interesting, well-structured, and valuable to readers and it can be considered for publication in the journal of Colloids and Interfaces after some small modifications:

1. Line 363: Liposome is one type of vesicle.

It has been deleted.

2. Line 408. Instead of strategy could it be better to say preparation method?

It has been done such.

3. The use of a table in which the main applications of hybrid colloids, regarding type of NP and polymers used, preparation method, size and shape.

We did not prefer adding a table, cause it overlaps with what stated.

Reviewer 2 Report

This review paper presents the concept of hybrid in colloid sciences, and the work is well presented. Therefore, I recommend publication of this manuscript, provided some minor revisions.

1. The meaning/purpose of Pi/Pmax between line 297 and 298 is unclear. Please address this accordingly
2. Figure 7: please add scale
3. Sub-section 4.1, line 425 to 430: at the end of this paragraph a), please include a specific example of a NP and a polymer, and how they bond together through covalent bonding (meaning which specific reactive surface group of the NP reacts with which specific complementary group of the polymer)
4. The title of section 2 is highlighted in bold but then the authors present sub-sections 3.1, 3.2, etc. Are you missing the title of section 3 (highlighted in bold) or are the sub-sections 3.1, 3.2, etc. actually supposed to be 2.1, 2.2, etc.?
5. The authors go from sub-section 3.4 to sub-section 4.1. Are you missing the title of section 4 (highlighted in bold)?
6. Figure 5: please add a visible scale (both bar and value)

Author Response

This review paper presents the concept of hybrid in colloid sciences, and the work is well presented. Therefore, I recommend publication of this manuscript, provided some minor revisions.

1. The meaning/purpose of Pi/Pmax between line 297 and 298 is unclear. Please address this accordingly.

The term P_i/P_max has been deleted.

2. Figure 7: please add scale.

It has been added.

3. Sub-section 4.1, line 425 to 430: at the end of this paragraph a), please include a specific example of a NP and a polymer, and how they bond together through covalent bonding (meaning which specific reactive surface group of the NP reacts with which specific complementary group of the polymer).

This has been done, stating that silica and octadecanol is a cogent example.

4. The title of section 2 is highlighted in bold but then the authors present sub-sections 3.1, 3.2, etc. Are you missing the title of section 3 (highlighted in bold) or are the sub-sections 3.1, 3.2, etc. actually supposed to be 2.1, 2.2, etc.?

Please add before 3.1 a title termed 3. More remarks.

5. The authors go from sub-section 3.4 to sub-section 4.1. Are you missing the title of section 4 (highlighted in bold)?

Yes. Please add  as a title 4. Materials Preparation.

6. Figure 5: please add a visible scale (both bar and value).

It has been added.