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Using Resistin, Glucose, Age and BMI and Pruning Fuzzy Neural Network for the Construction of Expert Systems in the Prediction of Breast Cancer

1
Information Systems Course—Centro Universitário UNA de Betim, Minas Gerais 32.510-010, Brazil
2
Federal Center for Technological Education of Minas Gerais, Minas Gerais 30.421-169, Brazil
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Mach. Learn. Knowl. Extr. 2019, 1(1), 466-482; https://doi.org/10.3390/make1010028
Received: 23 January 2019 / Revised: 4 February 2019 / Accepted: 12 February 2019 / Published: 14 February 2019
(This article belongs to the Special Issue Machine Learning for Biomedical Data Processing)
Research on predictions of breast cancer grows in the scientific community, providing data on studies in patient surveys. Predictive models link areas of medicine and artificial intelligence to collect data and improve disease assessments that affect a large part of the population, such as breast cancer. In this work, we used a hybrid artificial intelligence model based on concepts of neural networks and fuzzy systems to assist in the identification of people with breast cancer through fuzzy rules. The hybrid model can manipulate the data collected in medical examinations and identify patterns between healthy people and people with breast cancer with an acceptable level of accuracy. These intelligent techniques allow the creation of expert systems based on logical rules of the IF/THEN type. To demonstrate the feasibility of applying fuzzy neural networks, binary pattern classification tests were performed where the dimensions of the problem are used for a model, and the answers identify whether or not the patient has cancer. In the tests, experiments were replicated with several characteristics collected in the examinations done by medical specialists. The results of the tests, compared to other models commonly used for this purpose in the literature, confirm that the hybrid model has a tremendous predictive capacity in the prediction of people with breast cancer maintaining acceptable levels of accuracy with good ability to act on false positives and false negatives, assisting the scientific milieu with its forecasts with the significant characteristic of interpretability of breast cancer. In addition to coherent predictions, the fuzzy neural network enables the construction of systems in high level programming languages to build support systems for physicians’ actions during the initial stages of treatment of the disease with the fuzzy rules found, allowing the construction of systems that replicate the knowledge of medical specialists, disseminating it to other professionals. View Full-Text
Keywords: breast cancer; fuzzy neural network; pruning method; pattern classification breast cancer; fuzzy neural network; pruning method; pattern classification
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Silva Araújo, V.J.; Guimarães, A.J.; de Campos Souza, P.V.; Rezende, T.S.; Araújo, V.S. Using Resistin, Glucose, Age and BMI and Pruning Fuzzy Neural Network for the Construction of Expert Systems in the Prediction of Breast Cancer. Mach. Learn. Knowl. Extr. 2019, 1, 466-482.

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