Abstract
Chronic exposure of human skin to solar UV radiation is widely recognized as the main factor responsible for photoaging. The role of protection is essential to avoid skin cancer and other unwanted effects. The aim of the current study is to develop cosmetic formulations for sun protection based on silver nanoparticles (as an active ingredient) and natural extracts with high levels of bioactive compounds recovered from viticultural waste.
1. Introduction
The history of photoprotection dates back to ancient times, when the harmful influences and damage caused by long-term exposure to ultraviolet radiation were noticed. Over time, different products have been used, from natural products obtained from plants to synthesized chemical substances. Nowadays, the interest in these formulations is directed towards natural chemical compounds to avoid the use of harmful and hazardous compounds for humans and the environment.
2. Materials and Methods
In this paper, a cosmetic formulation for sun protection, based on silver nanoparticles and natural extracts from viticultural waste, was studied. The proposed material was obtained in the form of a hydrogel due to its emollient properties, non-greasy texture, ease of handling, compatibility with various excipients, and miscibility in water. The cosmetic formulation with sun protection and an antimicrobial effect was obtained based on an extract of vine shoots (from the Fetească Neagră Șt. variety, obtained by microwave-assisted extraction). The material was also characterized from an analytical point of view.
3. Results
The obtained results suggest that the obtained topic formulation presents a good antioxidant activity, antimicrobial activity (against Enterococcus faecalis, Pseudomonas aeruginosa ATCC 27853, Candida albicans ATTC 10231), and a medium sun factor protection.
4. Conclusions
The developed study reinforces the idea of using waste from the the agro sector to obtain value-added products.
Author Contributions
Conceptualization, A.M.B., I.F. and R.C.F.; methodology, A.M.B. and I.F.; formal analysis, R.C.F., L.-M.D., M.R., T.F. and R.I.M.; investigation, A.M.B., M.R., L.-M.D. and R.C.F.; writing—original draft preparation, A.M.B. and I.F.; writing—review and editing, A.M.B. and I.F.; supervision, I.F.; project administration, I.F. All authors have read and agreed to the published version of the manuscript.
Funding
The authors gratefully acknowledge the support of the Ministry of Research, Innovation and Digitization through Program 1—Development of the national research–development system, Subprogram 1.2—Institutional performance—Projects to finance excellence in RDI, Contract no. 15PFE/2021. The support provided by a grant of the Ministry of Research, Innovation and Digitization, CCCDI—UEFISCDI, project number PN-III-P2-2.1-PED-20210273, within PNCDI III, is also gratefully acknowledged.
Institutional Review Board Statement
Not applicable.
Informed Consent Statement
Not applicable.
Data Availability Statement
The supporting data are available from the corresponding author.
Conflicts of Interest
The authors declare no conflict of interest.
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