Next Article in Journal
Assessment of Quality of Life in Cancer Patients Undergoing Chemotherapy Treatment Using EORTC QLQ-C30 Questionnaire
Previous Article in Journal
Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Proceedings
Volume 88
Issue 1
10.3390/proceedings2023088004
proceedings-logo
Submit to this Journal
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Abstract

Effects of Vitamins C and E on Oxidative Stress among Diabetes Mellitus Type 2 Patients in Gaza City, Palestine †

by
Eman Seyam
1,*,
Marwan O. Jalambo
2 and
Mohammed Shubair
3
1
Master Program of Clinical Nutrition, Al-Azhar University Gaza (AUG), Gaza P.O. Box 405, Palestine
2
Nutrition Sciences and Public Health Program, Palestine Technical College, Deir Al-Balah P.O. Box 6037, Palestine
3
Faculty of Pharmacy, Al-Azhar University Gaza (AUG), Gaza P.O. Box 00970, Palestine
*
Author to whom correspondence should be addressed.
†
Presented at the Second International Conference on Applied Medical Sciences 2023 (ICAMS-II) and the International Conference on Enhancing Clinical Nutrition in Palestine (ECNAD), Gaza, Palestine, 14–16 March 2023.
Proceedings 2023, 88(1), 4; https://doi.org/10.3390/proceedings2023088004
Published: 28 July 2023
Versions Notes

Abstract

:
Oxidative stress is defined as the excessive production of reactive oxygen species (ROS) and reactive nitrogen species in the presence of diminished antioxidant substances. It has been shown that oxidative stress disrupts the normal glucose metabolism in type 2 diabetic patients. The authors aimed to study the effect of vitamins C and E on oxidative stress among diabetes mellitus Type 2 patients in Gaza City, Palestine. The purpose of this study was to evaluate the effects of vitamins C and vitamin E as an adjunctive therapy in reducing the Erythrocyte Sedimentation Rate, Malondialdehyde (MDA), hs-CRP, and Total cholesterol in the sera of type 2 diabetes mellitus patients in Gaza City. To achieve this study, one hundred and sixty-eight (168) diabetic patients were selected from Gaza City. The diabetic patients (117) were treated with anti-diabetic agents such as metformin and divided into three groups; the first group was a control group that received anti-diabetic agents metformin only; the second group received vitamin C (1000 mg) along with metformin; whereas the third group received vitamin C (1000 mg) and vitamin E (400 mg), together along with metformin. All patients were followed up for 3 months. The results showed more significant reductions in the MDA, Hs-CRP, and cholesterol levels among the patients who used vitamin C and combinations of vitamins C and E compared to those of the control group after 3 months. The reduction of MDA is larger in the vitamin C and E group than it was in the vitamin C group alone, and the reduction in cholesterol was similar in both groups, but there was not any improvement in the level of ESR. The study revealed that the use of antioxidants like vitamin C and vitamin E can decrease the severity of oxidative stress and decrease the level of inflammatory markers, and it improves the total cholesterol level, so antioxidants can improve diabetes mellitus and its complications.

Author Contributions

Conceptualization, E.S. and M.O.J.; methodology, M.O.J.; and M.S.; software, M.O.J.; validation, E.S., M.O.J. and M.S.; formal analysis, M.O.J.; investigation, M.O.J.; resources, E.S.; data curation, E.S. and M.O.J.; writing—original draft preparation, E.S.; writing—review and editing, E.S., M.O.J. and M.S.; visualization, E.S. and M.O.J.; supervision, M.O.J. and M.S.; project administration, M.O.J. and M.S. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Informed consent was obtained from all study sample involved in the study.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Seyam, E.; Jalambo, M.O.; Shubair, M. Effects of Vitamins C and E on Oxidative Stress among Diabetes Mellitus Type 2 Patients in Gaza City, Palestine. Proceedings 2023, 88, 4. https://doi.org/10.3390/proceedings2023088004

AMA Style

Seyam E, Jalambo MO, Shubair M. Effects of Vitamins C and E on Oxidative Stress among Diabetes Mellitus Type 2 Patients in Gaza City, Palestine. Proceedings. 2023; 88(1):4. https://doi.org/10.3390/proceedings2023088004

Chicago/Turabian Style

Seyam, Eman, Marwan O. Jalambo, and Mohammed Shubair. 2023. "Effects of Vitamins C and E on Oxidative Stress among Diabetes Mellitus Type 2 Patients in Gaza City, Palestine" Proceedings 88, no. 1: 4. https://doi.org/10.3390/proceedings2023088004

APA Style

Seyam, E., Jalambo, M. O., & Shubair, M. (2023). Effects of Vitamins C and E on Oxidative Stress among Diabetes Mellitus Type 2 Patients in Gaza City, Palestine. Proceedings, 88(1), 4. https://doi.org/10.3390/proceedings2023088004

Article Metrics

Back to TopTop