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Extended Abstract

Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases †

1
CBIOS—Research Centre for Biosciences & Health Technologies, Universidade Lusófona, Campo Grande 376, 1749-024 Lisbon, Portugal
2
Department of Biomedical Sciences, Faculty of Pharmacy, University of Alcalá, Ctra. A2, Km 33.600—Campus Universitario, 28871 Alcalá de Henares, Spain
3
iMed.ULisboa—Research Institute for Medicines and Pharmaceutical Sciences, Universidade de Lisboa—Faculdade de Farmácia, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal
4
Department of Organic & Inorganic Chemistry, Faculty of Pharmacy, University of Alcalá, 28801 Alcalá de Henares, Spain
*
Author to whom correspondence should be addressed.
Presented at the 1st International Electronic Conference on Biosensors, 2–17 November 2020; Available online: https://iecb2020.sciforum.net/.
Proceedings 2020, 60(1), 34; https://doi.org/10.3390/IECB2020-07090
Published: 14 November 2020
(This article belongs to the Proceedings of The 1st International Electronic Conference on Biosensors)

Abstract

:
Presently, long-lasting health disorders represent a significant health problem in developing countries. Further, epidemiological trends associated with lifestyle habits suggest that chronic conditions tend not to slow down all over the world. As such, reliable analytical techniques to manage chronic health conditions such as diabetes-mellitus, cardiovascular diseases and neurodegenerative diseases, among other non-communicable diseases (NCD), are of paramount importance.

The electrochemical biosensor is a pivotal technique for low analyte concentration detection, aiming for a swift and accurate diagnosis/therapy, to deal with the various health conditions [1]. However, the performance of electro-biosensors heavily depends on the catalytic activity of the material used as biosensor transducer. As a result, nanomaterials are widely used on the electrode surface owing to their unique physicochemical characteristics, such as their high surface area to volume ratio, which renders their features convenient for biosensing heterogeneous catalysts [2].
Nowadays, silver nanoparticles (AgNPs) are used in numerous biomedical applications, such as therapeutic purposes or as catalytic material in electrochemical analysis. Notwithstanding AgNPs health benefits, the conventional methods used in their synthesis are far from healthy, and scientific researchers are pursuing eco-friendly alternatives without health-hazardous chemicals [3].
One of the most-used alternatives is plant-assisted synthesis, using phytochemicals of the genus Plectranthus (Lamiaceae family) that are proving to be a remarkable reducing and stabilizing agent of well-dispersed metal nanoparticles [4].
The aim of the current study is the design of a skilled approach for the provision of Plectranthus-assisted AgNPs, suggesting their application as high-performance catalytic materials in a sensitive biosensor for NCD.

References

  1. Morais, A.L.; Rijo, P.; Hernán, M.B.B.B.; Nicolai, M. Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review. Biosensors 2020, 10, 121. [Google Scholar] [CrossRef] [PubMed]
  2. Morais, A.; Salgado, J.; Šljukić, B.; Santos, D.M.F.; Sequeira, C. Electrochemical behaviour of carbon supported Pt electrocatalysts for H2O2 reduction. Int. J. Hydrog. Energy 2012, 37, 14143–14151. [Google Scholar] [CrossRef]
  3. Khan, S.U.; Saleh, T.A.; Wahab, A.; Khan, M.H.U.; Khan, D.; Khan, W.U.; Rahim, A.; Kamal, S.; Khan, F.U.; Fahad, S. Nanosilver: New ageless and versatile biomedical therapeutic scaffold. Int. J. Nanomed. 2018, 13, 733–762. [Google Scholar] [CrossRef] [PubMed]
  4. Zheng, Y.; Huang, Y.; Shi, H.; Fu, L. Green biosynthesis of ZnO nanoparticles by Plectranthus amboinicus leaf extract and their application for electrochemical determination of norfloxacin. Inorg. Nano Met. Chem. 2019, 49, 277–282. [Google Scholar] [CrossRef]
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MDPI and ACS Style

Morais, A.L.; Rijo, P.; Batanero, B.; Nicolai, M. Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases. Proceedings 2020, 60, 34. https://doi.org/10.3390/IECB2020-07090

AMA Style

Morais AL, Rijo P, Batanero B, Nicolai M. Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases. Proceedings. 2020; 60(1):34. https://doi.org/10.3390/IECB2020-07090

Chicago/Turabian Style

Morais, Ana Lúcia, Patrícia Rijo, Belén Batanero, and Marisa Nicolai. 2020. "Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases" Proceedings 60, no. 1: 34. https://doi.org/10.3390/IECB2020-07090

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