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Open AccessAbstract

Challenges of Recruiting and Retaining African Women in HIV Vaccine Clinical Trials

1
Public Health and Epidemiology Department, Nigerian Institute of Medical Research, P.M.B 2013, Yaba, Lagos, Nigeria
2
Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, P.M.B 2013, Yaba, Lagos, Nigeria
*
Author to whom correspondence should be addressed.
Presented at the 5th African Conference on Emerging Infectious Diseases, Abuja, Nigeria, 7–9 August 2019.
Proceedings 2020, 45(1), 1; https://doi.org/10.3390/proceedings2020045001
Published: 8 March 2020
(This article belongs to the Proceedings of The 5th African Conference on Emerging Infectious Diseases)
One of the most urgent global public health needs is the development of a safe, effective, and accessible HIV vaccine. The ethical imperative demands that the situation of those people and population most vulnerable to exposure of HIV infection be addressed, especially women who are disproportionately affected by the infection. Participation of women in testing appropriate products is imperative and therefore the need for the recruitment and retention of African women in HIV vaccine clinical trials is of significance. The recruitment and retention of women in sub Saharan Africa who are vulnerable due to some factors beyond their control such as Biological, socio-cultural and socio-economic factors are further entangled in a number of challenges. These challenges include but not limited to Community participation consideration which vary within and between cultures. Other challenges are consent issues which should be freely given but could be influenced by coercion from husbands. Confidentiality that should be absolute for men and women is a more critical issue for women in Africa since they may need the permission of their husbands to participate in the study. Enrolment and retention of women in HIV vaccine clinical trials is an important challenge to the successful development of an effective vaccine. Therefore there is need for researchers to identify the various challenges and retention strategies through community involvement and representation before inception of clinical trials and ensure that the needs of this population are respected.
Keywords: women; HIV; clinical trial women; HIV; clinical trial
MDPI and ACS Style

Adewale, B.; Uwalaka, C.; Rahman, O.; Gambari, A. Challenges of Recruiting and Retaining African Women in HIV Vaccine Clinical Trials. Proceedings 2020, 45, 1.

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