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Abstract

Focusing on the Chemical Characterization, Antioxidant and Cytotoxic Properties of Two Geophytes: Crocus Pallasii and Cyclamen Cilicium †

by
Gokhan Zengin
1,* and
Evren Yildiztugay
2
1
Department of Biology, Science Faculty, Selcuk University, 42130 Konya, Turkey
2
Department of Biotechnology, Science Faculty, Selcuk University, 42130 Konya, Turkey
*
Author to whom correspondence should be addressed.
†
Presented at the 3rd International conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 18–20 December 2019.
Proceedings 2019, 40(1), 17; https://doi.org/10.3390/proceedings2019040017
Published: 25 December 2019
(This article belongs to the Proceedings of The 3rd International conference on Natural Products for Cancer Prevention and Therapy)
Versions Notes

Abstract

:
Species of the Crocus and Cyclamen genus have been reported to possess diverse biological properties. In the current work, the antioxidant and cytotoxic effects of the methanolic extracts of C. pallasii and C. cilicium aerial and underground parts were evaluated. The flower extracts of C. pallasii and C. cilicium possessed highest flavonoid content. Highest phenolic content was recorded from C. cilicium root extract (47.62 mg gallic acid equivalent/g extract). C. cilicium root extract showed significantly (p < 0.05) high radical scavenging (94.28 and 139.60 mg trolox equivalent [TE]/g extract, against DPPH and ABTS radicals, respectively) and reducing potential (173.30 and 109.53 mg TE/g extract, against CUPRAC and FRAP, respectively). Methanolic extracts of C. pallasii and C. cilicium showed toxicity against breast cancer cell lines. In the light of the above findings, C. cilicium might be considered as an interesting candidate in the development of anti-cancer agent, possessing antioxidant properties.

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MDPI and ACS Style

Zengin, G.; Yildiztugay, E. Focusing on the Chemical Characterization, Antioxidant and Cytotoxic Properties of Two Geophytes: Crocus Pallasii and Cyclamen Cilicium. Proceedings 2019, 40, 17. https://doi.org/10.3390/proceedings2019040017

AMA Style

Zengin G, Yildiztugay E. Focusing on the Chemical Characterization, Antioxidant and Cytotoxic Properties of Two Geophytes: Crocus Pallasii and Cyclamen Cilicium. Proceedings. 2019; 40(1):17. https://doi.org/10.3390/proceedings2019040017

Chicago/Turabian Style

Zengin, Gokhan, and Evren Yildiztugay. 2019. "Focusing on the Chemical Characterization, Antioxidant and Cytotoxic Properties of Two Geophytes: Crocus Pallasii and Cyclamen Cilicium" Proceedings 40, no. 1: 17. https://doi.org/10.3390/proceedings2019040017

APA Style

Zengin, G., & Yildiztugay, E. (2019). Focusing on the Chemical Characterization, Antioxidant and Cytotoxic Properties of Two Geophytes: Crocus Pallasii and Cyclamen Cilicium. Proceedings, 40(1), 17. https://doi.org/10.3390/proceedings2019040017

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