Evaluation of Laboratories Supporting Invasive Bacterial Vaccine-Preventable Disease (IB-VPD) Surveillance in the World Health Organization African Region, through the Performance of Coordinated External Quality Assessment
Abstract
:1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
3.1. General Description
3.2. Performance of Laboratories That Tested the Partial Panel: SSLs and NLs
3.3. Performance of Laboratories That Tested the Full Panel: RRLs and Selected SSLs and NLs
4. Discussion
5. Study Limitations
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Samples | Test Requested | Intended Result to be Reported (Partial Panel) | Intended Result to be Reported (Full Panel) |
---|---|---|---|
Slide smear | Gram staining | Cellular morphologies | |
Viable culture | Culture and species identification | Phenotypic or genotypic identification (Serogrouping or serotyping optional and not scored) | Phenotypic or genotypic identification Serogrouping or serotyping * |
Antimicrobial sensitivity testing | MIC results (if available) and S/I/R results, according to each participant’s local guidelines, for a predefined list of appropriate antibiotics (not scored) | ||
Simulated cerebrospinal fluid (CSF) | PCR testing | (Not included in the partial panel) | Genotypic identification * Genogrouping or genotyping * |
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Mandomando, I.; Mwenda, J.M.; Nakamura, T.; de Gouveia, L.; von Gottberg, A.; Kwambana-Adams, B.A.; Antonio, M.; Messa, A., Jr.; Litt, D.; Seaton, S.; et al. Evaluation of Laboratories Supporting Invasive Bacterial Vaccine-Preventable Disease (IB-VPD) Surveillance in the World Health Organization African Region, through the Performance of Coordinated External Quality Assessment. Trop. Med. Infect. Dis. 2023, 8, 413. https://doi.org/10.3390/tropicalmed8080413
Mandomando I, Mwenda JM, Nakamura T, de Gouveia L, von Gottberg A, Kwambana-Adams BA, Antonio M, Messa A Jr., Litt D, Seaton S, et al. Evaluation of Laboratories Supporting Invasive Bacterial Vaccine-Preventable Disease (IB-VPD) Surveillance in the World Health Organization African Region, through the Performance of Coordinated External Quality Assessment. Tropical Medicine and Infectious Disease. 2023; 8(8):413. https://doi.org/10.3390/tropicalmed8080413
Chicago/Turabian StyleMandomando, Inacio, Jason M. Mwenda, Tomoka Nakamura, Linda de Gouveia, Anne von Gottberg, Brenda A. Kwambana-Adams, Martin Antonio, Augusto Messa, Jr., David Litt, Shila Seaton, and et al. 2023. "Evaluation of Laboratories Supporting Invasive Bacterial Vaccine-Preventable Disease (IB-VPD) Surveillance in the World Health Organization African Region, through the Performance of Coordinated External Quality Assessment" Tropical Medicine and Infectious Disease 8, no. 8: 413. https://doi.org/10.3390/tropicalmed8080413