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Immunological Assays used to Support Efficacy of Zika Virus Vaccines

Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910, USA
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(3), 97;
Received: 15 May 2019 / Revised: 11 June 2019 / Accepted: 21 June 2019 / Published: 28 June 2019
(This article belongs to the Special Issue Developing Zika Vaccines: Status Update)
PDF [213 KB, uploaded 28 June 2019]


In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discuss published scientific efforts associated with these novel vaccines, emphasizing the immunological assays used to evaluate their immunogenicity and efficacy, and support future licensure. View Full-Text
Keywords: Zika; virus; vaccine; assays Zika; virus; vaccine; assays
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Eckels, K.H.; De La Barrera, R.A.; Putnak, J.R. Immunological Assays used to Support Efficacy of Zika Virus Vaccines. Trop. Med. Infect. Dis. 2019, 4, 97.

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Trop. Med. Infect. Dis. EISSN 2414-6366 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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