Next Article in Journal
The Global Burden of Disease of Zoonotic Parasitic Diseases: Top 5 Contenders for Priority Consideration
Next Article in Special Issue
Ultrastructural Features of Human Liver Specimens from Patients Who Died of Dengue Hemorrhagic Fever
Previous Article in Journal
A One Health Approach to Investigating Leptospira Serogroups and Their Spatial Distributions among Humans and Animals in Rio Grande do Sul, Brazil, 2013–2015
Previous Article in Special Issue
Comparison of Knowledge, Attitude, and Practice among Communities Living in Hotspot and Non-Hotspot Areas of Dengue in Selangor, Malaysia
Article Menu

Export Article

Open AccessCommunication

The First Outbreak of Dengue Fever in Greater Darfur, Western Sudan

1
Institute of Endemic Diseases, University of Khartoum, Khartoum 11111, Sudan
2
Department of Vector Biology, Liverpool School of Tropical Medicine (LSTM), Liverpool L3 5QA, UK
3
Epidemiology Department, National Public Health Laboratory, Khartoum 11111, Sudan
4
Health Emergencies and Epidemics Control Directorate, Sudan Federal Ministry of Health, Khartoum 11111, Sudan
5
Department of Biological Sciences, Ohio University, Zanesville, OH 45701, USA
*
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(1), 43; https://doi.org/10.3390/tropicalmed4010043
Received: 31 December 2018 / Revised: 15 February 2019 / Accepted: 27 February 2019 / Published: 1 March 2019
(This article belongs to the Special Issue Epidemiology of Dengue: Past, Present and Future)
  |  
PDF [1177 KB, uploaded 1 March 2019]
  |  

Abstract

Dengue virus (DENV) is an arthropod-borne virus (arbovirus) transmitted by the Aedes mosquitoes, mainly Aedes aegypti. Dengue fever is a rapidly growing disease with expanding geographical distribution worldwide. We investigated a high number of non-malaria febrile cases reported to health clinics in refugee camps in the five states of Darfur between August 2015 and March 2016. The clinical presentation of cases and case definition criteria suggested involvement of one or more arboviral hemorrhagic fevers. Out of 560 suspected cases, we collected and analyzed 204 blood samples and serologically positive samples were confirmed by PCR. We identified 32 (15.7%) dengue viral infections, six West Nile virus infections, and three Crimean–Congo viral infections. Dengue infections were found in four out of the five Darfur states. We reported the first dengue fever outbreak in the Darfur region. Our results highlight the need for public health education and further molecular, phylogenetic, and entomological investigations for a better understanding of the disease transmission and the associated risk factors in the region. View Full-Text
Keywords: dengue; outbreak; emergence; West Nile virus (WNV); hemorrhagic fever; Crimean–Congo hemorrhagic fever (CCHF); epidemic; Aedes aegypti; Greater Darfur; Sudan dengue; outbreak; emergence; West Nile virus (WNV); hemorrhagic fever; Crimean–Congo hemorrhagic fever (CCHF); epidemic; Aedes aegypti; Greater Darfur; Sudan
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Ahmed, A.; Elduma, A.; Magboul, B.; Higazi, T.; Ali, Y. The First Outbreak of Dengue Fever in Greater Darfur, Western Sudan. Trop. Med. Infect. Dis. 2019, 4, 43.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Trop. Med. Infect. Dis. EISSN 2414-6366 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top