Space and place are key concepts for understanding the functionality of social and environmental interactions. Cities are complex social-ecological systems where space–place interactions can be interpreted by means of quality of life. Firstly, we present several quality-of-life concepts that can be linked to space and place concepts. Secondly, we develop an analysis about space and place interactions, and how the social aspects, such as the sense of place, and physical aspects, such as urban spaces, are associated with quality of life and inclusive places. Thirdly, we state how the quality of life definitions of livability and life-ability are linked to the space and place concepts, and how this link can support the understanding of quality of life in cities, considering spatial thinking. Fourthly, we expand geo-information theories to a space–place approach of urban quality of life. Finally, we discuss how the developed conceptual framework can be applied to interpret the smart city. This paper contributes to the construction of new epistemologies that could support a more holistic understanding of the cities and a more social and humanistic use of geo-information and technology.
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