Effects of Passive Movement on Motor Function and Disability in Patients with Stroke: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Method
2.1. Inclusion and Exclusion Criteria
2.2. Searching the Literature
2.3. Selection of Eligible Studies and Data Extraction
2.4. Risk of Bias and Methodological Quality Assessments of the Included Studies
2.5. Data Synthesis
2.6. The Interpretation of the Evidence from the Findings
3. Results
3.1. Narrative Synthesis
3.1.1. Selection of Eligible Studies
3.1.2. The Characteristics of the Included Studies
3.1.3. Methodological Quality and Risks of Bias
3.2. Quantitative Synthesis
3.2.1. Recovery of Function
3.2.2. The Interpretation of the Evidence
4. Discussion
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
Appendix A
PubMED | (((((Stroke) OR (Ischaemic stroke)) OR (Hemorrhagic stroke)) OR (Brain infarction)) AND (Exercise)) AND ((((Range of motion) OR (passive range of motion)) OR (joint range of motion)) OR (joint flexibility)) Filters: Humans: English; RCTs; Adults |
Author Contributions: WoS | (((((Stroke) OR (Ischaemic stroke)) OR (Hemorrhagic stroke)) OR (Brain infarction)) AND (Exercise)) AND ((((Range of motion) OR (passive range of motion)) OR (joint range of motion)) OR (joint flexibility)) Filters: Stroke; Rehabilitation; English; Trials; Web of Science citation index (expanded and emerging); WoS conference citation index |
Embase | (((((Stroke) OR (Ischaemic stroke)) OR (Hemorrhagic stroke)) OR (Brain infarction)) AND (Exercise)) AND ((((Range of motion) OR (passive range of motion)) OR (joint range of motion)) OR (joint flexibility)) Filters: English; RCTs; cerebrovascular accident |
CENTRAL | (((((Stroke) AND (Exercise)) AND ((((Range of motion) OR (passive range of motion)) OR (joint range of motion)) Filters: CINAHL; English; Trials |
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PICOS Category | Inclusion Criteria | Exclusion Criteria |
---|---|---|
P (population) | Studies on males or females with stroke who are 18 years or older, within any stage of stroke | Studies not on patients with stroke |
I (intervention) | Passive movement of joints | Unclearly described passive movement |
C (comparators) | Any intervention or sham other than passive movement | Unclearly described intervention |
O (outcomes) | Recovery outcomes such as motor function and disability | Outcomes that are not reported to be valid and reliable |
S (study design) | Randomized controlled trial (RCT) | Study designs other than RCTs |
References | N | Stroke Duration | Mean Age (Years) | Intervention | Outcomes | Findings | Adverse Events |
---|---|---|---|---|---|---|---|
Lynch et al. [26] | N = 32; experimental (n = 17, females = 12); control (n = 15, females = 7) | Experimental = 14.0 + 2.0 days; control = 12.0 + 2.0 days | Experimental = 61.0 + 3.0; control = 71.0 + 3.0 | Participants in both groups received standard interdisciplinary therapy for 3.5 hrs per day. Experimental = received 25 min daily continuous passive motion comprising shoulder elevation, external rotation, and abduction, 5 times a week. Control 2 = performed group self-range of motion focused on goal-directed movements of the shoulder. | Level of motor impairment (FMA); motor function of shoulder and elbow (MSS); muscle power of wrist and hand (MPS); disability (FIM); joint pain (FMA pain index); shoulder joint stability; muscle tone (MAS). | No significant difference between groups in the outcomes of interest post intervention (at discharge). | Not reported |
Kim et al. [27] | N = 37 experimental (n = 19, females = 5); control (n = 18, females = 10) | Not reported | Experimental = 59.2 ± 14.1; control = 63.0 ± 16.2 | Experimental = performed 15 min bilateral passive ROM exercise of the upper limb joints twice a day, 5 days per week for 4 weeks. Each movement was repeated 10 times during the session. Control = performed same exercise as in the experimental group, but only after 2 weeks. | Upper extremity oedema (tape measure); ROM (goniometry); motor function (MFT); disability | All outcomes improved more significantly in the experimental group compared to the control post intervention. | Not reported |
Hosseini et al. [28] | N = 52; experimental (n = 33, females = 16); control (n = 19, females = 10) | Not reported | Experimental = 30–90; control = 30–90 | Experimental = performed 15–40 min passive ROM exercise of the upper limb joints 6 to 8 times. Control = received only routine care during the period. | Muscle strength (MRC scale). | Significant improvement in muscle strength in the experimental group. | Not reported |
Cho and Park [29] | N = 45; experimental 1 (n = 15, females = 5); experimental 2 (n = 15, females = 5); control (n = 15, females = 2) | Experimental 1 = 64.53 + 8.05; experimental 2 = 64.66 + 5.32; control = 63.40 + 7.09 | Experimental 1 = 3rd stage of the joint mobilization (gliding) was performed to induce dorsiflexion of the ankle joint repeatedly for 15 min. Control = performed active stretching of the ankle joint, repeated for 15 min. Experimental 2 = received a combined joint mobilization in experimental group 1 and the active stretching in the control group for 15 min. Intervention was done for 6 weeks. | ROM (goniometer); cadence, gait velocity and stride length (Gait–Walk). | All outcomes improved in the experimental groups. However, the improvement was more significant in the experimental group 2 (a combination of group experimental 1 and control group intervention). | Not reported |
Study | Eligibility Criteria Specified | Random Allocation | Concealed Allocation | Comparable Subjects | Blind Subjects | Blind Therapists | Blind Assessors | Adequate Follow-Up | Intention to Treat Analysis | Between Group Comparison | Point Estimation and Variability | Total Score |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lynch et al. [26] | Yes | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 5/10 |
Kim et al. [27] | Yes | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 7/10 |
Hosseini et al. [28] | Yes | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5/10 |
Cho and Park [29 | Yes | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 7/10 |
Number of Participants | |||||||||
---|---|---|---|---|---|---|---|---|---|
Outcome | Number of Studies | Risks of Bias | Inconsistency | Indirectness | Imprecision | Experimental | Control | Effect Size (95% CI) | Overall Certainty of the Evidence |
Motor function | 2 | Serious | Very serious a | Not serious | Serious b | 36 | 33 | 0.70 (0.21 to 1.18) | ⨁⨁◯◯ Moderate |
Muscle strength | 2 | Serious | Very serious a | Not serious | Serious b | 50 | 34 | 1.07 (−0.61 to 2.74) | ⨁⨁◯◯ Moderate |
Disability | 2 | Serious | Very serious a | Not serious | Serious b | 36 | 33 | 0.81 (0.32 to 1.31) | ⨁⨁◯◯ Moderate |
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Abdullahi, A.; Wong, T.W.L.; Ng, S.S.M. Effects of Passive Movement on Motor Function and Disability in Patients with Stroke: A Systematic Review and Meta-Analysis. J. Funct. Morphol. Kinesiol. 2025, 10, 117. https://doi.org/10.3390/jfmk10020117
Abdullahi A, Wong TWL, Ng SSM. Effects of Passive Movement on Motor Function and Disability in Patients with Stroke: A Systematic Review and Meta-Analysis. Journal of Functional Morphology and Kinesiology. 2025; 10(2):117. https://doi.org/10.3390/jfmk10020117
Chicago/Turabian StyleAbdullahi, Auwal, Thomson W. L. Wong, and Shamay S. M. Ng. 2025. "Effects of Passive Movement on Motor Function and Disability in Patients with Stroke: A Systematic Review and Meta-Analysis" Journal of Functional Morphology and Kinesiology 10, no. 2: 117. https://doi.org/10.3390/jfmk10020117
APA StyleAbdullahi, A., Wong, T. W. L., & Ng, S. S. M. (2025). Effects of Passive Movement on Motor Function and Disability in Patients with Stroke: A Systematic Review and Meta-Analysis. Journal of Functional Morphology and Kinesiology, 10(2), 117. https://doi.org/10.3390/jfmk10020117