Pre-Procedure Thrombocytopenia and Leukopenia Association with Risk for Infection in Image-Guided Tunneled Central Venous Catheter Placement
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Procedure
2.3. Data Collection and Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Positive Blood Cultures n = 25 | No Positive Blood Culture n = 152 | |
---|---|---|
Age | 23–75 mean 53.3 | 17–85 mean 53.0 |
Male | 14 (56.0%) | 93 (61.2%) |
Female | 11 (44.0%) | 59 (38.8%) |
Tunneled CVCs | 19 (76.0%) | 77 (50.7%) |
Non-tunneled CVCs | 6 (24.0%) | 75 (49.3%) |
Catheter French | 12–14.5 | 12–16 |
Underlying Diagnosis | Hematologic (n = 15): - Leukemia (n = 7) - Lymphoma (n = 4) - Other (n = 4) Renal (n = 10): - Acute kidney injury (n = 4) - CKD/ESRD (n = 6) | Hematologic (n = 48) - Lymphoma (n = 2) - Leukemia (n = 31) - Stem cell donor (n = 7) - Other (n = 8) Renal (n = 77): - Acute kidney injury (n = 31) - CKD/ESRD (n = 46) Neuro (n = 14) - Encephalitis (n = 3) - Inflammatory polyneuropathy (n = 4) - Myositis (n = 3) - Other inflammatory disorder (n = 4) Other (n = 13): - Solid organ transplant rejection (n = 10) - Other (n = 3) |
Reason for CVC | - Bone marrow transplant (n = 13) - Stem cell collection (n = 2) - Hemodialysis (n = 10) | - Plasmapheresis (n = 25) - Bone marrow transplant (n = 14) - Stem cell collection (n = 31) - Hemodialysis (n = 78) - Other: (n = 4) |
Pre-Procedural Antibiotics Given | Already Receiving Antibiotics | No Antibiotics Given | |
---|---|---|---|
Positive blood cultures and tunneled CVC n= 19 | 15 (78.9%) | 3 (15.8%) | 1 (5.3%) |
No positive blood culture and tunneled CVC n= 77 | 62 (80.5%) | 11 (14.3%) | 4 (5.2%) |
Positive blood cultures and non-tunneled CVC n= 6 | 0 (0%) | 0 (0%) | 6 (100.0%) |
No positive blood cultures and non-tunneled CVC n= 75 | 1 (1.3%) | 0 (0%) | 74 (98.7%) |
Positive Blood Cultures n = 19 | No Positive Blood Culture n = 77 | p Value | |
---|---|---|---|
WBC | |||
Mean (sd) | 4.53 ± 3.08 | 9.55 ± 8.22 | p = 0.01 |
Median | 4.05 | 7.86 | |
Range | 0.51–12.87 | 2.25–60.11 | |
Hemoglobin | |||
Mean (sd) | 10.50 ± 2.17 | 10.61 ± 2.58 | p = 0.86 |
Median | 10.20 | 10.3 | |
Range | 22.10–44.3 | 6.5–19.0 | |
Hematocrit | |||
Mean (sd) | 31.85 ± 6.13 | 32.81 ± 7.98 | p = 0.62 |
Median | 31.70 | 31.8 | |
Range | 22.10–44.30 | 18.5–58.9 | |
Platelets | |||
Mean (sd) | 150 ± 84.93 | 209.54 ± 100.93 | p = 0.02 |
Median | 181 | 197 | |
Range | 12–270 | 32–541 |
Patients with Positive Blood Cultures n = 6 | Patients without Positive Blood Cultures n = 75 | p Value | |
---|---|---|---|
WBC | |||
Mean (sd) | 9.74 ± 10.27 | 23.10 ± 68.13 | p = 0.63 |
Median | 7.61 | 11.31 | |
Range | 1.55–29.97 | 2.44–593.52 | |
Hemoglobin | |||
Mean (sd) | 8.77 ± 1.6 | 11.22 ± 2.32 | p = 0.01 |
Median | 8.35 | 11.4 | |
Range | 7.2–11.7 | 3.94–15.9 | |
Hematocrit | |||
Mean (sd) | 27.33 ± 5.86 | 34.61 ± 6.76 | p = 0.01 |
Median | 25.75 | 35.1 | |
Range | 22.2–38.7 | 19.3–35.1 | |
Platelets | |||
Mean (sd) | 125.82 ± 75.05 | 212.85 ± 111.34 | p = 0.06 |
Median | 112.5 | 197 | |
Range | 26–247 | 6–487 |
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Luman, A.; Quencer, K.B.; Kaufman, C. Pre-Procedure Thrombocytopenia and Leukopenia Association with Risk for Infection in Image-Guided Tunneled Central Venous Catheter Placement. Tomography 2022, 8, 627-634. https://doi.org/10.3390/tomography8020052
Luman A, Quencer KB, Kaufman C. Pre-Procedure Thrombocytopenia and Leukopenia Association with Risk for Infection in Image-Guided Tunneled Central Venous Catheter Placement. Tomography. 2022; 8(2):627-634. https://doi.org/10.3390/tomography8020052
Chicago/Turabian StyleLuman, Abigail, Keith B. Quencer, and Claire Kaufman. 2022. "Pre-Procedure Thrombocytopenia and Leukopenia Association with Risk for Infection in Image-Guided Tunneled Central Venous Catheter Placement" Tomography 8, no. 2: 627-634. https://doi.org/10.3390/tomography8020052